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首页> 外文期刊>Annals of Human Genetics >Phylogeography of the Y-chromosome haplogroup C in northern Eurasia.
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Phylogeography of the Y-chromosome haplogroup C in northern Eurasia.

机译：欧亚大陆北部Y染色体单倍群C的系统记录。

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摘要

To reconstruct the phylogenetic structure of Y-chromosome haplogroup (hg) C in populations of northern Eurasia, we have analyzed the diversity of microsatellite (STR) loci in a total sample of 413 males from 18 ethnic groups of Siberia, Eastern Asia and Eastern Europe. Analysis of SNP markers revealed that all Y-chromosomes studied belong to hg C3 and its subhaplogroups C3c and C3d, although some populations (such as Mongols and Koryaks) demonstrate a relatively high input (more than 30%) of yet unidentified C3* haplotypes. Median joining network analysis of STR haplotypes demonstrates that Y-chromosome gene pools of populations studied are characterized by the presence of DNA clusters originating from a limited number of frequent founder haplotypes. These are subhaplogroup C3d characteristic for Mongolic-speaking populations, "star cluster" in C3* paragroup, and a set of DYS19 duplicated C3c Y-chromosomes. All these DNA clusters show relatively recent coalescent times (less than 3000 years), so it is probable that founder effects, including social selection resulting in high male fertility associated with a limited number of paternal lineages, may explain the observed distribution of hg C3 lineages.
机译：为了重建欧亚大陆北部人口的Y染色体单倍群（hg）C的系统发育结构，我们分析了西伯利亚，东亚和东欧18个种族的413名男性中的微卫星（STR）基因座的多样性。 。对SNP标记的分析表明，尽管一些人群（例如蒙古族和科里亚克族）显示出相对较高的输入（超过30％）尚未确定的C3 *单倍型，但所有研究的Y染色体均属于汞C3及其亚单元组C3c和C3d。 STR单倍型的中位连接网络分析表明，所研究人群的Y染色体基因库的特征在于存在来自数量有限的频繁建立者单倍型的DNA簇。这些是说蒙古语的人群的亚单元组C3d特征，C3 *旁群中的“星团”和一组DYS19复制的C3c Y染色体。所有这些DNA簇都显示出相对较近的合并时间（少于3000年），因此创始人效应（包括社会选择导致与少数父系血统相关的高男性生育力）可能可以解释hg C3血统的分布。

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