Controlling Field-Effect Transistor Biosensor Electrical Characteristics Using Immunosorbent Assay

Vaknin O.; Khamaisi B.; Mizrahi M.; Ashkenasy N.

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Controlling Field-Effect Transistor Biosensor Electrical Characteristics Using Immunosorbent Assay

机译：使用免疫吸附测定法控制场效应晶体管生物传感器的电气特性

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A method to modulate the signal of field-effect transistor biosensors using an immunosorbent assay is described. A model system is used to show that binding of a secondary antibody, to which highly charged gold colloids are attached, to an analyte on the device floating gate can be used to induce strong electrostatic effects, which affect the device threshold voltage and source-drain current. This process may be used for signal amplification, with the secondary binding specificity allowing for improved signal to noise ratio, which is of great importance for early disease detection.

机译：描述了一种使用免疫吸附测定法调节场效应晶体管生物传感器信号的方法。使用模型系统可以显示，带有高电荷的金胶体的二抗与器件浮栅上的分析物的结合可用于诱导强烈的静电效应，从而影响器件的阈值电压和源极-漏极当前。此过程可用于信号放大，其二级结合特异性可提高信噪比，这对于早期疾病检测非常重要。

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来源
《Electroanalysis》 |2011年第10期|共8页
作者
Vaknin O.; Khamaisi B.; Mizrahi M.; Ashkenasy N.;
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正文语种 eng
中图分类电化学、电解、磁化学;
关键词
Amplification; Biosensors; Colloids; Field-effect transistors; Proteins;

机译：放大;生物传感器;胶体;场效应晶体管;蛋白质;

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1. Controlling Field-Effect Transistor Biosensor Electrical Characteristics Using Immunosorbent Assay [J] . Vaknin O., Khamaisi B., Mizrahi M., Electroanalysis . 2011,第10期

机译：使用免疫吸附测定法控制场效应晶体管生物传感器的电气特性
2. Electrical Characteristics of Doped Silicon Nanowire Channel Field-Effect Transistor Biosensors [J] . Taiuk Rim, Kihyun Kim, Hyeonsu Cho, Sensors Journal, IEEE . 2017,第3期

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3. A Comparative Study of Nitrogen Gas Flow Ratio Dependence on the Electrical Characteristics of Sputtered Titanium Nitride Gate Bulk Planar Metal-Oxide-Semiconductor Field-Effect Transistors and Fin-Type Metal-Oxide-Semiconductor Field-Effect Transistors [J] . Tetsuro Hayashida, Yongxun Liu, Takashi Matsukawa, Japanese journal of applied physics . 2009,第5issue2期

机译：氮流量比与溅射氮化钛栅体平面金属氧化物半导体场效应晶体管和鳍型金属氧化物半导体场效应晶体管电学特性的比较研究
4. Improved Electrical Characteristics of P-type Tunnel Field-Effect Transistor With Source-Pocket Junction Formed Using High-Angle Implantation [C] . Gaobo Xu, Huaxiang Yin, Qiuxia Xu, SOI-3D-Subthreshold Microelectronics Technology Unified Conference . 2019

机译：利用高角度植入形成的源极袋结改善了P型隧道场效应晶体管的电气特性
5. Functionalization and Characterization of Nanomaterial Gated Field-Effect Transistor-Based Biosensors and the Design of a Multi-Analyte Implantable Biosensing Platform. [D] . Croce, Robert A., Jr. 2012

机译：纳米材料门控基于场效应晶体管的生物传感器的功能化和表征，以及多分析物可植入生物传感平台的设计。
6. Study of zeolite influence on analytical characteristics of urea biosensor based on ion-selective field-effect transistors [O] . Margaryta K Shelyakina, Oleksandr O Soldatkin, Valentyna M Arkhypova, 2014

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7. Study of zeolite influence on analytical characteristics of urea biosensor based on ion-selective field-effect transistors [O] . Margaryta K Shelyakina, Oleksandr O Soldatkin, Valentyna M Arkhypova, 2014

机译：基于离子选择场效应晶体管的沸石对尿素生物传感器分析特性的影响研究

Controlling Field-Effect Transistor Biosensor Electrical Characteristics Using Immunosorbent Assay

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