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首页> 外文期刊>European journal of anaesthesiology >Intraoperative fetal oxygen saturation during Caesarean section: general anaesthesia using sevoflurane with either 100% oxygen or 50% nitrous oxide in oxygen.
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Intraoperative fetal oxygen saturation during Caesarean section: general anaesthesia using sevoflurane with either 100% oxygen or 50% nitrous oxide in oxygen.

机译：剖宫产术中胎儿的血氧饱和度：使用七氟醚与氧气中的100％氧气或50％一氧化二氮进行全身麻醉。

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BACKGROUND AND OBJECTIVE: The study was designed to evaluate whether the administration of sevoflurane in 100% oxygen for anaesthesia during Caesarean section would improve fetal and neonatal oxygenation compared with the administration of sevoflurane with 50% nitrous oxide in oxygen. METHODS: The randomized, single-blind controlled study examined 24 mothers, ASA I-II, at term undergoing Caesarean section who were allocated to receive sevoflurane in either 100% oxygen (n = 13) or 50% nitrous oxide in oxygen (n= 11). General anaesthesia was induced in both groups with thiopental 4-5 mg kg(-1) followed by succinylcholine 1.5 mg kg(-1) to facilitate tracheal intubation. Parturients received sevoflurane given either in 100% O2 or in a 50:50 nitrous oxide and oxygen mixture, using 0.5-1.0% progressive incremental dosing up to 1.5-2.0 MAC. Non-invasive fetal oxygen saturation was measured between induction to delivery, and umbilical artery and vein PaO2 were evaluated at birth. RESULTS: Intraoperative fetal oxygen saturation increased in all patients after maternal 100% oxygen administration (P < 0.01). Maternal hyperoxygenation significantly increased the umbilical vein and umbilical artery PaO2 and the umbilical artery SaO2 at birth (P < 0.0001). CONCLUSIONS: Maternal hyperoxygenation significantly improves fetal as well as neonatal oxygenation.
机译：背景与目的：本研究旨在评估与在氧气中使用50％一氧化二氮的七氟醚相比，在剖宫产术中以100％氧气进行七氟醚麻醉的麻醉是否会改善胎儿和新生儿的氧合。方法：这项随机，单盲对照研究对24例接受剖宫产的母亲ASA I-II进行了检查，这些母亲被分配接受100％氧气（n = 13）或50％一氧化二氮的氧气（n = 11）。两组均先行全身麻醉，先用硫喷妥钠4-5 mg kg（-1），然后再用琥珀酰胆碱1.5 mg kg（-1）进行气管插管。产妇接受100％O2或50:50的一氧化二氮和氧气混合物中的七氟醚，使用0.5-1.0％的渐进式递增剂量直至1.5-2.0 MAC。在诱导至分娩之间测量非侵入性胎儿氧饱和度，并在出生时评估脐动脉和静脉PaO2。结果：所有患者在产妇100％给予氧气后，术中胎儿的血氧饱和度均升高（P <0.01）。产妇的高氧显着增加了出生时的脐静脉和脐动脉PaO2以及脐动脉SaO2（P <0.0001）。结论：母体的高氧可显着改善胎儿以及新生儿的氧合。

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