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首页> 外文期刊>European journal of gynaecological oncology >Relationship between angiogenesis and grade of histologic differentiation in endometrial adenocarcinoma.
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Relationship between angiogenesis and grade of histologic differentiation in endometrial adenocarcinoma.

机译：子宫内膜腺癌的血管生成与组织学分化程度的关系。

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The objective of the study was to quantify vessels and to relate them to the degree of histologic differentiation in endometrial adenocarcinoma. We studied 35 cases of which ten were G1, 13 G2 and 12 G3 adenocarcinomas. The control group consisted of 11 atrophic and 10 proliferative endometria. From each case two histologic sections were obtained: one for hematoxylin-eosin staining and the other for immunohistochemical study with anti-CD34. Vessel count was performed by morphometric study. Mean vessel count was 15.3 for G1; 19 for G2 and 22.7 for G3 adenocarcinomas; in the control group it was 11.6 for atrophic and 13.2 for proliferative endometria. Slightly differentiated adenocarcinoma presented greater angiogenesis than normal and well-differentiated carcinoma. In contrast, moderately differentiated carcinoma showed greater angiogenicity as related to normal endometrium, but did not differ from other tumoral endometria.
机译：该研究的目的是量化血管并将其与子宫内膜腺癌的组织学分化程度联系起来。我们研究了35例G10、13 G2和12 G3腺癌。对照组由11个萎缩和10个增生性子宫内膜组成。从每个病例中获得两个组织学切片：一个用于苏木精-伊红染色，另一个用于用抗CD34进行免疫组织化学研究。通过形态计量学研究进行血管计数。 G1的平均血管计数为15.3; G2腺癌19例，G3腺癌22.7例;对照组萎缩性子宫内膜癌为11.6，增生性子宫内膜癌为13.2。轻度分化的腺癌比正常和高分化的癌具有更大的血管生成能力。相比之下，中分化的癌表现出与正常子宫内膜相关的更大的血管生成性，但与其他肿瘤子宫内膜无差异。

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