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首页> 外文期刊>Expert opinion on pharmacotherapy >Medical prevention of stroke and stroke recurrence in patients with TIA and minor stroke.
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Medical prevention of stroke and stroke recurrence in patients with TIA and minor stroke.

机译：TIA和轻度中风患者的中风和中风复发的医学预防。

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BACKGROUND: Secondary stroke prevention after transient ischemic stroke (TIA) or minor stroke is of major importance in order to avoid recurrent cerebrovascular events and decrease morbidity and mortality. OBJECTIVE/METHODS: Systematically review of recently published, high-quality studies emphasizing the need for emergency assessment and treatment of patients with TIA and minor stroke and to give a comprehensive and distinct overview over medical secondary stroke prevention trials performed in these patients. RESULTS/CONCLUSIONS: Evaluation and implementation of preventive stroke therapy has to be immediate in patients with TIA and stroke. For patients with non-cardioembolic stroke, antiplatelet agents are the treatment of choice. Aspirin plus extended-release dipyridamole and clopidogrel are more effective than aspirin and should be used in patients with a high risk of recurrent stroke. Oral anticoagulation is highly effective in patients with a cardiac source of embolism. Treatment of risk factors such as arterial hypertension and high cholesterol is even more important in secondary stroke prevention than in primary prevention. Vitamin supplementation and lowering of elevated levels of homocysteine are not effective in stroke prevention.
机译：背景：短暂性脑卒中（TIA）或轻度中风后的二级卒中预防对于避免脑血管复发和降低发病率和死亡率至关重要。目的/方法：系统地回顾最近发表的高质量研究，强调对TIA和轻度卒中患者进行紧急评估和治疗的必要性，并对这些患者进行的医学继发性卒中预防试验进行全面而独特的概述。结果/结论：TIA和中风患者必须立即评估和实施预防性中风治疗。对于非心脏栓塞性中风的患者，抗血小板药物是首选治疗方法。阿司匹林加缓释双嘧达莫和氯吡格雷比阿司匹林更有效，应用于复发性卒中高风险患者。患有心脏栓塞的患者口服抗凝药非常有效。在二级卒中预防中，对动脉高压和高胆固醇等危险因素的治疗比在一级预防中更为重要。补充维生素和降低高半胱氨酸水平对预防中风无效。

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