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Reproduction after breast cancer.

机译:乳腺癌后的生殖。

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摘要

Breast cancer is the most frequently occurring cancer in women of developed countries, and as a result of new developments in breast cancer treatment, more women are cured after being diagnosed with this disease. It is important that fertility preservation strategies are addressed before chemotherapy, because chemotherapy may induce premature ovarian failure (depending on the woman's age, the drugs used, the dosage and duration of treatment). Among possible solutions are embryos or oocytes cryopreservation, ovarian tissue cryopreservation-freezing with a subsequent orthotopic and heterotopic autotransplantation, whole ovary cryopreservation, ovarian suppression with gonadotropin-releasing hormone (GnRH) analogues, which inhibit ovarian follicular depletion induced by chemotherapeutic agents and in vitro fertilisation (IVF) after ovulation induction with aromatase inhibitors or tamoxifen.
机译:乳腺癌是发达国家妇女中最常见的癌症,并且由于乳腺癌治疗的新发展,更多的妇女被诊断出患有这种疾病后可以治愈。化疗之前必须解决生育保留策略,因为化疗可能会导致卵巢早衰(取决于女性的年龄,所用药物,治疗的剂量和持续时间),这一点很重要。可能的解决方案包括胚胎或卵母细胞冷冻保存,卵巢组织冷冻保存及随后的原位和异位自体移植,全卵巢冷冻保存,促性腺激素释放激素(GnRH)类似物对卵巢的抑制作用,这些抑制物可抑制化学治疗剂和体外诱导的卵泡消耗。用芳香酶抑制剂或他莫昔芬诱导排卵后进行受精(IVF)。

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