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THE TRANSMISSION OF FISH-PAINTED PATTERNS DERIVED FROM COMPLEX CHROMOSOME EXCHANGES

机译:复杂染色体交换衍生的鱼斑纹的传播

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摘要

The first 26 families of complex chromosome-type exchanges (from three breaks in two chromosomes to five breaks in five chromosomes) have been evaluated, and the 15 060 exchanges resulting from unrestricted restitution or rejoining of the break ends yields 203 distinctive patterns, if a single participating chromosome is FISH-painted. If we assume that any exchange that produces an acentric fragment of any sort (compound-terminal or interstitial) will be ultimately eliminated in a continuously dividing cell population, then, irrespective of family origin, only 17 of these patterns (approximate to 8%) will be transmitted, long-term.
机译:已评估了前26个复杂染色体类型交换的家族(从两个染色体中的三个断裂到五个染色体中的五个断裂),并且由于无限制地恢复或重新连接断裂末端而产生的15060个交换产生203个独特的模式,如果单个参与染色体涂有鱼。如果我们假设在连续分裂的细胞群体中最终会消除产生任何形式的无心片段(化合物末端或间隙)的任何交换,那么,不管家族起源如何,这些模式中只有17种(大约8%)会长期传播。

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