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Asthma and COPD in an Italian adult population: Role of BMI considering the smoking habit

机译：意大利成年人口中的哮喘和COPD：BMI考虑吸烟习惯的作用

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摘要

Smoking and body mass index (BMI) are well-documented risk factors that contribute substantially to chronic obstructive pulmonary disease (COPD) and asthma. However, the relations among smoking, obesity, and COPD or asthma remain to be clarified. We conducted a population-based cross-sectional epidemiologic study to explore the association between BMI and COPD or asthma among non-smokers, smokers and ex-smokers using information obtained from the Health Search database (HSD) owned by the Italian College of General Practitioners (SIMG), which stores information on about 1.5% of the total Italian population served by general practitioners (GPs). Our study confirms the importance of smoking status in patients with COPD, but not in those with asthma. Moreover, it demonstrates that the increase in BMI is frequently associated with the diagnosis of COPD or asthma, suggesting that the probability of suffering from COPD or asthma increases with the increase in body weight regardless of the smoking status. The association between an increase in BMI appears to be greater in women than in men. Our data also show that underweight is significantly associated with COPD, but only in men, while being underweight apparently protects from the possibility of suffering from asthma.
机译：吸烟和体重指数（BMI）是有据可查的危险因素，对慢性阻塞性肺疾病（COPD）和哮喘有重大影响。但是，吸烟，肥胖与COPD或哮喘之间的关系尚待阐明。我们进行了一项基于人群的横断面流行病学研究，使用从意大利全科医生学院拥有的健康搜索数据库（HSD）获得的信息，探索了非吸烟者，吸烟者和前吸烟者中BMI与COPD或哮喘之间的关联。 （SIMG），该信息存储着由全科医生（GP）服务的约1.5％的意大利总人口的信息。我们的研究证实了COPD患者吸烟状态的重要性，而哮喘患者则没有。此外，它表明BMI的升高通常与COPD或哮喘的诊断有关，这表明不管体重高低，吸烟者患COPD或哮喘的可能性都随着体重的增加而增加。女性体重指数增加与男性之间的关联似乎更大。我们的数据还表明，体重不足与COPD显着相关，但仅在男性中，体重不足显然可以预防哮喘的发生。

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