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Pulmonary hypertension responding to hyperthyroidism treatment.

机译:对甲状腺功能亢进症治疗有反应的肺动脉高压。

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摘要

Pulmonary hypertension in adults with hyperthyroidism is increasingly being reported. Although the mechanism is uncertain, the reversal of pulmonary hypertension following restoration to an euthyroid state supports a causal relationship. This case report is of a 43-year-old woman who presented with Graves disease and right ventricular failure. Echocardiography showed severe pulmonary hypertension, moderate to severe tricuspid regurgitation, normal left heart function and a negative bubble contrast study. Carbimazole therapy was instituted along with diuretics and captopril. The patient was followed for a period of 14 months. Clinical and biochemical euthyroidism was attained after 4 months of treatment. Resolution of right ventricular failure and normalization of pulmonary artery pressure occurred 11 and 14 months after initiation of therapy, respectively. Investigating thyroid status in patients with pulmonary hypertension is recommended. In patients with hyperthyroidism and (otherwise unexplained) pulmonary hypertension, restoration of euthyroidism may cure right ventricular failure and restore normal pulmonary artery pressure.
机译:成人甲亢患者肺动脉高压的报道越来越多。尽管机制尚不确定,但恢复到正常甲状腺状态后肺动脉高压的逆转支持因果关系。该病例报告是一名患有Graves病和右心衰竭的43岁女性。超声心动图显示严重肺动脉高压,中度至重度三尖瓣关闭不全,左心功能正常以及气泡对比研究阴性。与利尿剂和卡托普利一起建立了咔唑治疗。对该患者进行了14个月的随访。治疗4个月后达到临床和生化甲状腺功能正常。开始治疗后11个月和14个月,右心衰竭的缓解和肺动脉压力的恢复正常。建议调查肺动脉高压患者的甲状腺状况。患有甲状腺功能亢进和(否则无法解释)肺动脉高压的患者,恢复甲状腺功能正常可以治愈右心室衰竭并恢复正常的肺动脉压。

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