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首页> 外文期刊>Rhinology >Kinetics of olfactory function following endonasal sinus surgery for nasal polyposis.
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Kinetics of olfactory function following endonasal sinus surgery for nasal polyposis.

机译：鼻息肉鼻窦手术后嗅觉功能的动力学。

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INTRODUCTION: Sinus surgery is known to improve olfactory function in patients with nasal polyposis. However, little is known about the kinetics of this process. MATERIAL AND METHODS: Fifty-two adult patients with nasal polyposis underwent endonasal sinus surgery. Olfactory testing was performed with the Sniffin' Sticks assessing threshold (T), discrimination (D) and identification (I) giving the TDI score. Testing was performed 2 days prior to surgery (T1), as well as 1 week (T2), 1 month (T3), 3 months (T4), and 6 months (T5) following surgery. RESULTS: The median TDI score was 15.4 (range 8.0-35.5) at T1, indicating that half the patients were anosmic before surgery, while 13.5% were normosmic. At T2, the median TDI score dropped to 8.0 (range 8.0-32.1). Thereafter, it improved to 21.7 (range 8.0-36.9) at T3 (p = 0.04), 22.8 (range 8.0-38.0) at T4 (p < 0.0005), and 27.0 (range 8.0-37.9) at T5 (p < 0.0005), respectively. 43.1% of patients were normosmic at T5, however, 21.6% remained anosmic. Each subtest followed the same pattern. No significant effect on the kinetics of olfactory function could be found for variables such as systemic steroids, partial resection of the middle turbinate, inferior turbinotomy, and allergic rhinitis. CONCLUSION: Endonasal sinus surgery significantly improved the severely impaired olfactory function in patients with nasal polyposis. Olfactory function dropped shortly after surgery, and subsequently increased steadily up to the endpoint of the study 6 months postoperatively.
机译：简介鼻窦手术可改善鼻息肉病患者的嗅觉功能。但是，对该过程的动力学知之甚少。材料与方法：52例成人鼻息肉患者接受了鼻内窦手术。嗅觉测试通过嗅嗅棒评估阈值（T），辨别力（D）和鉴定（I）得出TDI得分。在手术前2天（T1），手术后1周（T2），1个月（T3），3个月（T4）和6个月（T5）进行测试。结果：在T1时，TDI的中位数为15.4（范围8.0-35.5），表明一半的患者在手术前厌食，而13.5％的患者为正常。在T2，TDI的中位数降至8.0（范围为8.0-32.1）。之后，它在T3（p = 0.04）改善到21.7（范围8.0-36.9），在T4（p <0.0005）改善到22.8（范围8.0-38.0），在T5（p <0.0005）改善到27.0（范围8.0-37.9）。 ， 分别。 43.1％的患者在T5时是正常的，但仍有21.6％的患者处于厌氧状态。每个子测试遵循相同的模式。对于诸如系统性类固醇，中鼻甲部分切除，下鼻甲切开术和变应性鼻炎等变量，未发现对嗅觉动力学的显着影响。结论：鼻内鼻窦手术显着改善了鼻息肉病患者严重的嗅觉功能。手术后不久，嗅觉功能下降，并在术后6个月达到研究终点。

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