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Bidirectional Doppler Fourier-domain optical coherence tomography for measurement of absolute flow velocities in human retinal vessels

机译:双向多普勒傅里叶域光学相干断层扫描技术,用于测量人视网膜血管中的绝对流速

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We describe a bidirectional color Doppler Fourier-domain optical coherence tomography system capable of measuring absolute velocities of moving scatterers by illuminating the sample with two linearly and orthogonally polarized beams, incident at a known angle on the sample. The velocity calculation is independent of the exact orientation of the velocity vector in the detection plane. First measurements were performed on a rotating disk driven at well-defined velocities and tilted by various small angles. Our results indicate a high correlation between preset and calculated velocities (correlation coefficient 0.999) and the independency of these velocities from the tilting angle of the disk. We demonstrate that bidirectional color Doppler optical coherence tomography allows for the measurement of absolute blood flow values in vivo in human retinal vessels.
机译:我们描述了一种双向彩色多普勒傅里叶域光学相干断层扫描系统,该系统能够通过以两个已知角度入射到样品上的线性和正交偏振光束照射样品,从而测量运动散射体的绝对速度。速度计算与速度矢量在检测平面中的确切方向无关。第一次测量是在以明确的速度驱动并倾斜各种小角度的旋转磁盘上进行的。我们的结果表明,预设和计算的速度(相关系数0.999)与这些速度与光盘倾斜角度的独立性之间具有高度相关性。我们证明了双向彩色多普勒光学相干断层扫描技术可以测量人体视网膜血管中的体内绝对血流值。

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