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Factors associated with arthrogenous muscle inhibition in patellofemoral osteoarthritis

机译：tell股骨关节炎中与人工肌肉抑制有关的因素

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Objectives: Arthrogenous muscle inhibition (AMI) is thought to contribute to quadriceps weakness in knee osteoarthritis (OA), but its relationship with structural changes of bone marrow lesions (BMLs), capsular distension and pain is unclear. This study's objective was to investigate the factors associated with AMI in subjects with symptomatic patellofemoral joint OA (PFJOA). Design: 126 Subjects with predominant PFJOA were assessed for pain by the visual analogue scale (VAS) for a nominated aggravating activity. Their more symptomatic knee underwent amagnetic resonance imaging (MRI) scan which was used to assess BMLs and synovitis which were scored using the Whole Organ MRI score (WORMS). Quadriceps AMI was measured by calculating the activation deficit and quadriceps strength assessed by isometric maximum voluntary contraction. Multiple linear regressions were used to assess factors associated with AMI. Results: We studied 124 subjects [mean age 55.5 (SD 7.5); 57.14% female]. In regression analyses, higher levels of AMI were significantly associated with more severe knee pain and with lower BML score. Conclusion: Quadriceps AMI in knee OA is associated with severity of knee pain and surprisingly with lower BML scores.
机译：目的：人工肌肉抑制（AMI）被认为是导致股四头肌无力的原因，但与骨髓病变（BML），囊膜扩张和疼痛的结构变化之间的关系尚不清楚。这项研究的目的是调查有症状的pa股关节OA（PFJOA）患者与AMI相关的因素。设计：用视觉模拟量表（VAS）评估了126名以PFJOA为主的受试者的疼痛加重活动。他们对有症状的膝盖进行了磁共振成像（MRI）扫描，该扫描用于评估BML和滑膜炎，并使用全器官MRI评分（WORMS）对其进行评分。股四头肌AMI通过计算激活不足和通过等轴测最大自主收缩评估的股四头肌力量来测量。多元线性回归用于评估与AMI相关的因素。结果：我们研究了124名受试者[平均年龄55.5（SD 7.5）; 57.14％女]。在回归分析中，较高水平的AMI与更严重的膝关节疼痛和较低的BML评分显着相关。结论：膝骨关节炎中的股四头肌AMI与膝关节疼痛的严重程度有关，并且出乎意料的是其BML评分较低。

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