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Eating Disorders in Schizophrenia: Implications for Research and Management

机译：精神分裂症的饮食失调：对研究和管理的启示

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Objective. Despite evidence from case series, the comorbidity of eating disorders (EDs) with schizophrenia is poorly understood. This review aimed to assess the epidemiological and clinical characteristics of EDs in schizophrenia patients and to examine whether the management of EDs can be improved. Methods. A qualitative review of the published literature was performed using the following terms: "schizophrenia" in association with "eating disorders," "anorexia nervosa," "bulimia nervosa," "binge eating disorder," or "night eating syndrome." Results. According to our literature review, there is a high prevalence of comorbidity between schizophrenia and EDs. EDs may occur together with or independent of psychotic symptoms in these patients. Binge eating disorders and night eating syndromes are frequently found in patients with schizophrenia, with a prevalence of approximately 10%. Anorexia nervosa seems to affect between 1 and 4% of schizophrenia patients. Psychopathological and neurobiological mechanisms, including effects of antipsychotic drugs, should be more extensively explored. Conclusions. The comorbidity of EDs in schizophrenia remains relatively unexplored. The clearest message of this review is the importance of screening for and assessment of comorbid EDs in schizophrenia patients. The management of EDs in schizophrenia requires a multidisciplinary approach to attain maximized health outcomes. For clinical practice, we propose some recommendations regarding patient-centered care.
机译：目的。尽管从病例系列中获得了证据，但人们对饮食失调与精神分裂症的合并症知之甚少。这篇综述旨在评估精神分裂症患者中EDs的流行病学和临床特征，并检查是否可以改善EDs的管理。方法。使用以下术语对出版的文献进行定性审查：“精神分裂症”与“饮食失调”，“神经性厌食症”，“神经性贪食症”，“暴饮暴食症”或“夜间进食综合征”。结果。根据我们的文献综述，精神分裂症和ED之间合并症的患病率很高。在这些患者中，ED可能与精神病症状同时出现或独立于精神病症状而出现。精神分裂症患者经常发现暴饮暴食症和夜间进食综合征，患病率约为10％。神经性厌食似乎影响了1％至4％的精神分裂症患者。应更广泛地探索心理病理和神经生物学机制，包括抗精神病药的作用。结论EDs在精神分裂症中的合并症尚待开发。该评价最明确的信息是筛查和评估精神分裂症患者合并症ED的重要性。精神分裂症急诊室的管理需要多学科的方法来实现最大程度的健康结果。对于临床实践，我们提出了一些以患者为中心的护理建议。

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