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首页> 外文期刊>Surgical Endoscopy >Gastrointestinal transit and stress response after laparoscopic vs conventional distal pancreatectomy in the canine model.
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Gastrointestinal transit and stress response after laparoscopic vs conventional distal pancreatectomy in the canine model.

机译：在犬模型中，腹腔镜与常规远端胰切除术相比，胃肠道转运和应激反应。

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BACKGROUND: Several authors have presented the feasibility of laparoscopic pancreatic surgery. However, the pathophysiological effect of laparoscopic pancreatic surgery is not well known. METHODS: Ten mongrel dogs were randomly operated for laparoscopic and conventional distal pancreatectomy. Fed state gastrointestinal transit times were assessed using radiopaque markers. To assess surgical stress, we determined serum IL-1 and cortisol. RESULTS: Postoperative mouth-to-anus transit time in the laparoscopic group was not prolonged while it was significantly prolonged in the conventional group compared with the baseline study, but no significant differences between groups were detected. First defecation was observed significantly earlier in the laparoscopic group. Serum cortisol levels were elevated significantly at 4 h after skin incision in both groups and decreased thereafter. In the laparoscopic group, they returned close to the normal level at 8 h after incision, but were still significantly higher in the conventional group. The level of IL-1 was elevated significantly higher in conventional group at 24 h after the skin incision. CONCLUSION: Thus, we conclude that laparoscopic distal pancreatectomy demonstrated faster recovery of the bowel transit and less stress than conventional distal pancreatectomy in dogs.
机译：背景：几位作者提出了腹腔镜胰腺手术的可行性。然而，腹腔镜胰腺手术的病理生理作用尚不清楚。方法：随机将十只杂种犬进行腹腔镜和常规远端胰腺切除术。使用不透射线的标记物评估进食状态胃肠道的通过时间。为了评估手术压力，我们确定了血清IL-1和皮质醇。结果：与基线研究相比，腹腔镜组术后口到肛门的穿刺时间没有延长，而常规组明显延长了，但是两组之间没有发现显着差异。首次排便在腹腔镜组中观察到较早。两组皮肤切开后4 h，血清皮质醇水平显着升高，此后降低。在腹腔镜组，切口后8 h他们恢复到接近正常水平，但在常规组中仍显着更高。皮肤切开术后24 h，常规组IL-1水平明显升高。结论：因此，我们得出的结论是，与常规的远端胰脏切除术相比，腹腔镜远端胰脏切除术表现出更快的肠运输恢复和更少的压力。

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