...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>PACE: Pacing and clinical electrophysiology >The impact of QT lag compensation on dynamic assessment of ventricular repolarization: reproducibility and the impact of lead selection.
【24h】

The impact of QT lag compensation on dynamic assessment of ventricular repolarization: reproducibility and the impact of lead selection.

机译：QT滞后补偿对心室复极动态评估的影响：可再现性和导线选择的影响。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In cardiac disease, abnormalities exist in the rate-corrected QT interval and the relationship between QT and heart rate. The QT/RR relationship is known to be dynamic and show circadian variation. The availability of automated methods for measurement of QT and RR intervals allows monitoring of the QT/RR relationship and may provide insights into arrhythmia onset. Using a method for analyzing 24-hour recordings that incorporates beat-by-beat QT and RR measurement and an automated mechanism for compensating for lag in adaptation of QT to changes in RR, the authors evaluated the impact of lag compensation on assessment of the QT/RR relationship, reproducibility, and the effect of lead selection in 15 normal subjects. The QT/RR relationship is continuously estimated from the lag compensated data over a 5-minute scrolling time frame. The relationship is expressed as an exponential formula, QT = QTo.RRJ where QTo is the QT interval at a standardized RR interval of 1 second and J is a variable exponent. We found that the use of lag compensation significantly improves the mean 24-hour correlation between QT and RR data (r = 0.87 vs 0.65). The 24-hour mean of QTo and J were highly reproducible (coefficients of variation 2% and 8%, respectively). The mean 24-hour QT/RR relationship for the population was QT = 0.415.(RR)0.32. There was a small difference between leads in QTo and J. Compensating for QT adaptation lag provides a means of assessing the QT/RR relationship over long and short periods. This method allows investigation of the effect of acute interventions on the dynamic QT/RR relationship, which has previously been restricted by the presence of QT hysteresis.
机译：在心脏病中，在校正后的QT间隔以及QT与心率之间的关系中存在异常。 QT / RR关系是动态的，并显示昼夜节律变化。用于测量QT和RR间隔的自动方法的可用性允许监视QT / RR关系，并且可以提供有关心律失常发作的见解。通过使用一种结合逐拍QT和RR测量以及用于补偿QT适应RR变化的延迟的自动机制的24小时记录分析方法，作者评估了滞后补偿对QT评估的影响/ RR关系，可重复性和15位正常受试者的铅选择效果。在5分钟的滚动时间范围内，根据滞后补偿数据连续估算QT / RR关系。该关系表示为指数公式QT = QTo.RRJ，其中QTo是标准RR间隔为1秒时的QT间隔，而J是可变指数。我们发现滞后补偿的使用显着改善了QT和RR数据之间的平均24小时相关性（r = 0.87 vs 0.65）。 QTo和J的24小时平均值具有很高的重现性（变异系数分别为2％和8％）。人群的平均24小时QT / RR关系为QT = 0.415。（RR）0.32。 QTo和J之间的引线之间存在很小的差异。补偿QT适应滞后提供了一种评估长期和短期QT / RR关系的方法。这种方法可以研究急性干预对动态QT / RR关系的影响，而动态QT / RR关系以前受到QT滞后现象的限制。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号