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首页> 外文期刊>Physiological Research >Comparative Dipolar Electrocardiotopographic Study of Ventricular Activation in Macaca mulatta Monkeys and Man
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Comparative Dipolar Electrocardiotopographic Study of Ventricular Activation in Macaca mulatta Monkeys and Man

机译：猕猴和人心室激活的比较偶极心电图研究

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摘要

Electrocardiographic correlates of ventricular activation sequence were studied in 22 Macaca mulatta monkeys, aged 1-18 years, and 145 human subjects, aged 11-72 years, using the corrected orthogonal lead system of McFee-Parungao and the dipolar electrocardiotopographic (DECARTO) data presentation, where the time series of instantaneous spatial vectors are converted into time series of areas of activation on a spherical image surface enveloping the heart. Macaques had shorter ventricular activation time (61?11 vs. 97?11 ms) that could not be explained exclusively by their higher heart rate. Their DECARTO image of the resultant activation front occurred 10 ms after QRS onset (septal activation) identically with humans, but it attained a more anteriorly oriented maximum earlier than in humans (20 vs. 40 ms). The time course of the extent of the resultant activation front in old macaques (15-18 years) resembled to that observed in humans. On the average, female macaques had smaller DECARTO images of activation fronts throughout the QRS complex than males. This finding is in agreement with the known smaller QRS amplitudes in women than in men.
机译：使用McFee-Parungao校正的正交导联系统和偶极心电地形图（DECARTO）数据展示，对22只1-18岁的猕猴和145只11-72岁的人类受试者的心室激活序列进行了心电图相关性研究。 ，其中瞬时空间矢量的时间序列被转换为包围心脏的球形图像表面上激活区域的时间序列。猕猴的心室激活时间较短（61？11 vs. 97？11 ms），这不能完全由其较高的心率来解释。他们产生的激活前沿的DECARTO图像与人类完全相同，发生在QRS发作后10毫秒（间隔激活），但比人类更早地达到了前向最大值（20 vs. 40 ms）。在老猕猴（15-18岁）中，合成活化前沿的程度的时程与在人类中观察到的相似。平均而言，雌性猕猴在整个QRS复合体中的激活前沿的DECARTO图像小于雄性。这一发现与女性比男性更小的QRS振幅相符。

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