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DEFECTIVE RECOMBINANT RETROVIRUS, ITS APPLICATION TO THE INTEGRATION OF CODING SEQUENCES FOR PROTEINS DETERMINED IN THE GENOME OF CORRESPONDING WILD RETROVIRUS INFECTIOUS CELLS AND RECOMBINANT DNA FOR THE PRODUCTION OF THIS RECOMBINANT RETROVIRUS
DEFECTIVE RECOMBINANT RETROVIRUS, ITS APPLICATION TO THE INTEGRATION OF CODING SEQUENCES FOR PROTEINS DETERMINED IN THE GENOME OF CORRESPONDING WILD RETROVIRUS INFECTIOUS CELLS AND RECOMBINANT DNA FOR THE PRODUCTION OF THIS RECOMBINANT RETROVIRUS
The invention relates to a defective recombinant retrovirus containing a coding sequence for a specific protein in the genome of cells. The DNA of the recombinant retrovirus contains the coding sequence for the protein interposed between a splice acceptor site and a splice donor site, the whole being placed under the control of an appropriate promoter, and this under conditions such as the infection of said cells by this recombinant retrovirus is accompanied by the incorporation of the coding sequence for the protein into the genome of the infected cells. /P
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