摘要:
Objective:To analyze the effect of potassium magnesium aspartate injection in the treatment of lo-cal limb spasm in the recovery period of cerebral hemorrhage.Methods:76 patients with cerebral hemorrhage at re-covery stage were randomly divided into control group and treatment group 38 cases.Control group took routine medical treatment:nutrition nerve,reduce muscle tension treatment(calf serum to protein injection 0.8 % sodium chloride injection 250 ml,once/d,vinpocetine injection of 20 mg of 0.9 % sodium chloride injection 250 ml intrave-nous drip,once/d;Oral eperisone hydrochloride 50m,3 times/d).In the control group,on the basis of the control group,adding potassium magnesium aspartate injection(Sinopharm,10ml/branch)30 ml into 5 % glucose injec-tion 250 ml,intravenous drip,once/d,treatment cycle 10 days.The modified ashworth scale,spastic frequency scale and Pittsburgh sleep quality index were used to evaluate the spasticity and sleep of the two groups before and after treatment.Results:the clinical efficacy,improved ashworth scale,spastic frequency scale and Pittsburgh sleep quality index were significantly improved in the treatment group compared with the control group(P< 0.05). Conclusion:potassium magnesium aspartate injection can improve the symptoms of local limb spasm in patients with cerebral hemorrhage recovery,indirectly improve the sleep situation and improve the quality of life of patients.%目的:分析门冬氨酸钾镁注射液治疗脑出血恢复期局部肢体痉挛的疗效.方法:将76例脑出血恢复期出现局部肢体痉挛患者随机分为对照组和治疗组各38例.对照组采取内科常规治疗:营养神经、降低肌张力治疗(小牛血清去蛋白注射液0.8g入0.9% 氯化钠注射液250 ml静滴,1次/d,长春西汀注射液20 mg入0.9% 氯化钠注射液250 ml静滴,1次/d;口服盐酸乙哌立松50mg,3次/d).治疗组在对照组治疗的基础上,增加门冬氨酸钾镁注射液(国药准字 H33020038, 10 ml/支)30 ml入5% 葡萄糖注射液250 ml,静滴,1次/d,治疗周期10 d.采用改良Ashworth量表、痉挛频率量表、匹茨堡睡眠质量指数对两组治疗前后肢体痉挛状态、睡眠情况作出评价.结果:治疗组在临床有效率、改良Ashworth量表评分、痉挛频率量表评分、匹茨堡睡眠质量指数评分方面较对照组均有明显改善,差异具有统计学意义(P<0.05).结论:门冬氨酸钾镁注射液能改善脑出血恢复期患者局部肢体痉挛的症状,间接改善患者睡眠情况,提高患者生活质量.