首页> 外文会议>Advanced bioactive compounds countering the effects of radiological, chemical and biological agents : Strategies to counter biological damage >The Protective Effects of Natural Polyphenolic Complexes of Grape Wine on Organisms Exposed to Oxidative and Nitrosative Stress Under Diabetes Mellitus
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The Protective Effects of Natural Polyphenolic Complexes of Grape Wine on Organisms Exposed to Oxidative and Nitrosative Stress Under Diabetes Mellitus

机译:葡萄酒中天然多酚复合物对糖尿病人氧化和亚硝化应激生物的保护作用

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摘要

Peripheral nerve damage is a significant complication of diabetes mellitus. The ingestion of polyphenols available naturally in a variety of plant products may provide impressive protection against such damage. The natural polyphenol complex of grape wine has a significant anti-diabetic effect. It can protect against dehydration at the level of the whole organism and deter free radical-induced damage to the sciatic nerve, the spinal cord, kidney and retina. The levels of nitrosylated and PARylated proteins can be restored to near control levels by the extract. The biochemical mechanisms of action of the natural polyphenol complex of grape wine require further research, but may be considered as a valuable therapeutic approach for the treatment of diabetic complications.
机译:周围神经损伤是糖尿病的重要并发症。摄入多种植物产品中天然存在的多酚可能会提供令人印象深刻的保护,以防止此类破坏。葡萄酒中的天然多酚复合物具有显着的抗糖尿病作用。它可以在整个生物体水平上防止脱水,并阻止自由基引起的对坐骨神经,脊髓,肾脏和视网膜的损害。提取物可将亚硝酰化和PAR酰化的蛋白质水平恢复到接近控制水平。葡萄酒中天然多酚复合物的生物化学作用机制需要进一步研究,但可以被认为是治疗糖尿病并发症的有价值的治疗方法。

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