首页> 中文期刊> 《中国神经精神疾病杂志》 >增强型体外反搏对缺血性卒中患者动脉弹性的影响

增强型体外反搏对缺血性卒中患者动脉弹性的影响

         

摘要

Objectives To examine the effects of enhanced external counterpulsation on arterial elasticity in stroke patients to provide clinical evidence for secondary prevention of patients with cerebral ischemic stroke. Methods Total 192 patients with ischemic stroke were enrolled and then divided into the EECP (n=107) and control (n=85) group. Auto-matic measurement synchronous atherosclerosis detector was use to measure brachial-ankle pulse wave velocity (BaP-WV) and cardio-ankle vascular index (CAVI). The difference of BaPWV and CAVI were evaluated before, at 36 hours and one month after EECP. Results The BaPWV and CAVI significantly decreased at 36 hours and 1 month after treat-ment in EECP groups compared to either pre-therapy or control groups (all P<0.05). Conclusions EECP can signifi-cantly reduce the BaPWV and CAVI and improve the arterial elasticity in patients with cerebral ischemic stroke. Thus, arterial elasticity may be an important index to evaluate the effects of EECP on cerebral ischemic stroke.%目的:定量评估增强型体外反搏(enhanced external counterpulsation, EECP)对缺血性卒中患者动脉弹性的影响,为缺血性卒中患者的二级预防及治疗提供进一步的临床证据。方法选取缺血性卒中住院患者共192例,其中EECP组107例,对照组85例,采用同步自动测量动脉硬化检测仪测定所有患者的肱踝脉搏波传导速度(brachial-ankle pulse wave velocity, BaPWV)以及心踝血管指数(cardio-ankle vascular index, CAVI),分别比较两组EECP治疗前、治疗36 h后、治疗结束后1个月的BaPWV及CAVI的差别。结果 EECP治疗36 h后和治疗后1个月与治疗前相比,BaPWV及CAVI均显著下降,差异均具有统计学意义(P<0.05);EECP治疗组与对照组相比,BaPWV及CAVI均显著下降,差异具有统计学意义(P<0.05)。对照组各时间点BaPWV及CAVI无明显变化,差异均无统计学意义(P>0.05)。结论 EECP治疗可降低缺血性卒中患者的BaPWV和CAVI水平,改善缺血性卒中患者的动脉弹性,且作用持久。

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