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Thrombolytic effects of Douchi Fibrinolytic enzyme from Bacillus subtilis LD-8547 in vitro and in vivo

机译：枯草芽孢杆菌LD-8547的豆chi纤溶酶的体内外溶栓作用

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摘要

BackgroundToday, thrombosis is one of the most widely occurring diseases in modern life. Drugs with thrombolytic functions are the most effective methods in the treatment of thrombosis. Among them, Douchi fibrinolytic enzyme (DFE) is a promising agent. DFE was isolated from Douchi, a typical and popular soybean-fermented food in China, and it can dissolve fibrin directly and efficiently. A strain, Bacillus subtilis LD-8547 produced DFE with high fibrinolytic activity has been isolated in our lab previously.

机译：背景技术如今，血栓形成是现代生活中最广泛发生的疾病之一。具有溶栓功能的药物是治疗血栓形成的最有效方法。其中，豆chi纤溶酶（DFE）是一种有前途的药物。 DFE是从豆chi中分离出来的，豆Dou是中国典型的大豆发酵食品，可以直接有效地溶解纤维蛋白。以前在我们实验室中已经分离出了具有高纤溶活性的枯草芽孢杆菌LD-8547菌株。

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期刊名称 BMC Biotechnology
作者
Jun Yuan; Jing Yang; Zhenhong Zhuang; Yanling Yang; Ling Lin; Shihua Wang;
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作者单位

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年(卷),期 2012(12),-1
年度 2012
页码 36
总页数 9
原文格式 PDF
正文语种
中图分类应用微生物学;
关键词
Thrombolytic effects Douchi Fibrinolytic enzyme in vitro in vivo;

机译：溶栓作用;Douchi纤溶酶;体外;体内;

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专利

1. Thrombolytic effects of Douchi Fibrinolytic enzyme from Bacillus subtilis LD-8547 in vitro and in vivo [J] . Jun Yuan, Jing Yang, Zhenhong Zhuang, BMC Biotechnology . 2012,第1期

机译：枯草芽孢杆菌LD-8547的豆chi纤溶酶的体内外溶栓作用
2. Screening of a high fibrinolytic enzyme producing strain and characterization of the fibrinolytic enzyme produced from Bacillus subtilis LD-8547 [J] . Wang Shi H., Zhang Cheng, Yang Yan L., World Journal of Microbiology & Biotechnology . 2008,第4期

机译：高产纤溶酶的菌株的筛选和枯草芽孢杆菌LD-8547产生的纤溶酶的表征
3. Screening of a high fibrinolytic enzyme producing strain and characterization of the fibrinolytic enzyme produced from Bacillus subtilis LD-8547 [J] . Shi H. Wang, Cheng Zhang, Yan L. Yang, World Journal of Microbiology and Biotechnology . 2008,第4期

机译：高产纤溶酶的菌株的筛选和枯草芽孢杆菌LD-8547产生的纤溶酶的表征
4. Fibrinolytic and anti-thrombotic effect of NKCP, the protein layer from Bacillus subtilis (natto) [C] . Kazonobu Omura, Masahito Hitosugi, Kazutoshi Kaketani, International Conference on Food Factors . 2004

机译：NKCP的纤维蛋白溶解和抗血栓形成效应，来自枯草芽孢杆菌（纳豆）的蛋白质层
5. Characterization of protein cross -links in the coats of Bacillus subtilis spores and analysis of spore coat rinds resistant to degradative enzymes* [D] . Carroll, Alicia Monroe 2008

机译：枯草芽孢杆菌孢子皮中蛋白质交联的表征以及对降解酶具有抗性的孢子皮果皮的分析*
6. Purification and characterization of a novel highly potent fibrinolytic enzyme from Bacillus subtilis DC27 screened from Douchi a traditional Chinese fermented soybean food [O] . Yuanliang Hu, Dan Yu, Zhaoting Wang, -1

机译：从中国传统发酵大豆食品豆chi中筛选的枯草芽孢杆菌DC27新型高效纤溶酶的纯化和鉴定
7. Thrombolytic effects of Douchi Fibrinolytic enzyme from Bacillus subtilis LD-8547 in vitro and in vivo [O] . Jun Yuan, Jing Yang, Zhenhong Zhuang, 2012

机译：枯草芽孢杆菌LD-8547的豆chi纤溶酶的体内外溶栓作用
8. Effects of Mutant Small, Acid-Soluble Spore Proteins from Bacillus Subtilis onDNA In vivo and In vitro [R] . Tovar-Rojo, F., Setlow, P. 1991

机译：枯草芽孢杆菌小，酸可溶性孢子蛋白对体内和体外DNa的影响

Thrombolytic effects of Douchi Fibrinolytic enzyme from Bacillus subtilis LD-8547 in vitro and in vivo

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