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The Isolation of Myristicin from Nutmeg Oil by Sequences Distillation

机译:顺序蒸馏从肉豆蔻油中分离肉豆蔻酸

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Background: Nutmeg oil is used in Asia as a traditional medicine for a stomach cramps, diarrhea, and insomnia. It’s quality need to be improved by increasing myristicin content. Objectives: This study aimed to increase the myristicin content of nutmeg oil by sequences distillations. Methods: Three different conditions of distillations were applied sequentially. The first, second and third distillation were at 1100C (0.2 bars), 1050C (1 bar), and 1450C (0.2 bars) respectively. Myristicin contents determined by gas chromatography-mass spectrometry (GC-MS). Results: the myristicin content of the original nutmeg oil, the first, the second, and the third distillation were 12.93%, 17.50%, 54.21%, and 83.45% respectively. The total yield of the final product resulted after the third distillation was 5.84% v/v from the original oil. Conclusion: The use of sequences distillation with a different condition can increase the myristicin content from the original nutmeg oil.
机译:背景:肉豆蔻油在亚洲用作胃痉挛,腹泻和失眠的传统药物。需要通过增加肉豆蔻苷含量来提高其质量。目的:本研究旨在通过顺序蒸馏增加肉豆蔻油中肉豆蔻苷的含量。方法:依次应用三种不同的蒸馏条件。第一次,第二次和第三次蒸馏分别在110 0 C(0.2 bar),105 0 C(1 bar)和145 0 C (0.2巴)。肉豆蔻苷含量通过气相色谱-质谱法(GC-MS)测定。结果:原始肉豆蔻油,第一次,第二次和第三次蒸馏中的肉豆蔻苷含量分别为12.93%,17.50%,54.21%和83.45%。第三次蒸馏后得到的最终产物的总产率为原始油的5.84%v / v。结论:在不同条件下使用顺序蒸馏可以增加肉豆蔻油中肉豆蔻苷的含量。

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