首页> 外文期刊>The biochemical journal >Medium-chain fatty acid synthesis in lactating-rabbit mammary gland. Intracellular concentration and specificity of medium-chain acyl thioester hydrolase
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Medium-chain fatty acid synthesis in lactating-rabbit mammary gland. Intracellular concentration and specificity of medium-chain acyl thioester hydrolase

机译:乳酸 - 兔乳腺中的中链脂肪酸合成。中链酰基乙酯水解酶的细胞内浓度和特异性

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pThe concentration of medium-chain acyl thioester hydrolase and of fatty acid synthetase was determined by rocket immunoelectrophoresis in nine different particle-free supernatant fractions from lactating-rabbit mammary gland. The molar ratio of the hydrolase to fatty acid synthetase was 1.99 +/- 0.66 (mean +/- S.D.). A rate-limiting concentration of malonyl-CoA was required to ensure the predominant synthesis of medium-chain fatty acids when 2 mol of the hydrolase was added per mol of fatty acid synthetase. The interaction of the hydrolase with fatty acid synthetase was concentration-dependent, though an optimum concentration of hydrolase to synthetase could not be obtained. The lactating-rabbit mammary gland hydrolase altered the pattern of fatty acids synthesized by fatty acid synthetases prepared from cow, goat, sheep and rabbit lactating mammary glands, rabbit liver and cow adipose tissue./p
机译:>通过来自乳酸兔乳腺的九个不同颗粒上清液馏分的火箭免疫电泳测定中链酰基酯水解酶和脂肪酸合成酶的浓度。水解酶与脂肪酸合成酶的摩尔比为1.99 +/- 0.66(平均值+/- S.D.)。当每摩尔脂肪酸合成酶加入2摩尔水解酶时,需要一种碱基-CoA的速率限制浓度。水解酶与脂肪酸合成酶的相互作用浓度依赖性,但不能获得与合成酶的最佳浓度浓度。乳酸兔乳腺水解酶改变了由牛,山羊,绵羊和兔哺乳哺乳动物,兔肝脏和牛脂肪组织制备的脂肪酸合成酶合成的脂肪酸的图案。

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    《The biochemical journal》 |1979年第2期|共页
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    J Knudsen;

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  • 收录信息 美国《科学引文索引》(SCI);
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