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Alternatives to Animal Testing and Experimentation

中文名称：替代动物实验和实验

ISSN：1344-0411
出版周期：Quarterly

发文量：144

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1.Assessment of the human Cell Line Activation Test(h-CLAT) for Skin Sensitization; Results of the First Japanese Inter-laboratory Study

机译：评估人类细胞系激活测试（h-CLAT）的皮肤敏感性;日本首个实验室间研究的结果
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2008年第1期
- Skin sensitization;
- alternatives;
- THP-1;
- reproducibility;
- h-CLAT;
2.A low cost and quick assay system using the free-living nematode Caenorhabditis elegans to determine the effects of Kampo medicines on life span

机译：使用线虫秀丽隐杆线虫的低成本，快速测定系统，确定Kampo药物对寿命的影响
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2008年第1期
- C. elegans;
- life span;
- Kampo medicines;
- crude drugs;
- oxidative stress;
3.Validation of human skin models for skin corrosivity tests in Japan

机译：在日本对人体皮肤模型进行皮肤腐蚀性测试的验证
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2008年第1期
- Skin corrosivity;
- cultured epidermal model;
- cultured skin model;
- validation;
4.Assessment of the in vitro skin irritaion by chemicals using the Vitrolife-Skin~(TM) human skin model

机译：使用Vitrolife-Skin〜（TM）人皮肤模型评估化学物质对皮肤的体外刺激
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2008年第1期
- human skin model;
- skin irritancy;
- Vitrolife-Skin~(TM);
- EPISKIN~(TM);
- ECVAM;
5.A study on serum difference on test results in the human Cell Line Activation Test (h-CLAT): Results of 3rd Japanese inter-laboratory study

机译：人体细胞系激活测试（h-CLAT）中测试结果的血清差异研究：第三个日本实验室间研究的结果
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2008年第2期
- skin sensitization;
- alternative test;
- serum;
- h-CLAT;
6.A Study of the Criteria for Selection of THP-1 Cells in the Human Cell Line Activation Test (h-CLAT): Results of 2nd Japanese Inter-laboratory Study

机译：人类细胞系激活测试（h-CLAT）中THP-1细胞选择标准的研究：第二项日本实验室间研究的结果
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2008年第2期
- h-CLAT;
- skin sensitization;
- alternatives;
- THP-1;
- cell selection;
7.Increasing the Implementation of Alternatives to Laboratory Animal Use

机译：增加对实验动物使用替代品的实施
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2008年第3期
- 3Rs;
- alternative;
- animal experiment;
- animal model;
- laboratory animal;
8.Cell Viability Test for Alkalinized Lidocaine using the Three-dimensional Cultured Human Skin Model

机译：使用三维培养的人类皮肤模型对碱化利多卡因的细胞活力测试
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2008年第3期
- lidocaine;
- human skin model;
- cell viability;
- Lidocaine;
9.An in Vitro Evaluation Method to Test Ocular Irritation using a Human Corneal Epithelium Model

机译：一种使用人角膜上皮模型测试眼刺激的体外评估方法
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2008年第2期
- ocular irritation;
- corneal model;
- Draize eye test;
- cytotoxicity assay;
- dose-dependency;
10.In Vitro Embryotoxicity Testing of Mercury Vapour by Differentiation of ES-D3 Cells

机译：ES-D3细胞分化对汞蒸气的体外胚胎毒性测试
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2008年第3期
- mercury vapour;
- embryotoxicity;
- ES cell;
11.Effects of pre-culture conditions on the human Cell Line Activation Test (h-CLAT) results: Results of the 4th Japanese inter-laboratory study

机译：培养前条件对人类细胞系激活测试（h-CLAT）结果的影响：第四项日本实验室间研究的结果
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2008年第2期
- h-CLAT;
- skin sensitization;
- alternatives;
- THP-1;
- culture;
12.The Formation of a New American Society to Implement Non-Animal Testing Methods

机译：实施非动物测试方法的新美国社会的形成
- 作者：Erin H. Hill
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第1期
13.Real-time Evaluation of Hemocompatible Materials by Human Platelets as an Alternative to Animal Experimentation

机译：人类血小板替代动物实验对血液相容性材料的实时评估
- 作者：Katsuko S Furukawa;Satoshi Seki;Yuki Hirano;Hanako Miki;Kazuyuki Mizuhara;Takashi Yamane;Tetsuya Tateishi;Takashi Ushida
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第1期
- human blood from bank;
- cone and plate-type rheometer;
- shear stress;
- small volume;
- hemocompatibility;
14.An Interlaboratory Collaborative Study on a Cell Transformation Assay Using Bhas 42 Cells

机译：利用Bhas 42细胞进行细胞转化实验的实验室间合作研究
- 作者：Noriho Tanaka;Kiyoshi Sasaki;Kumiko Hayashi;Ayako Sakai;Shin Asada;Dai Muramatsu;Sachiko Kuroda;Fukutaro Mizuhashi;Miho Nagai;Hiroshi Suzuki;Tadashi Imamura;Masumi Asakura;Hidetaka Satoh;Akiko Sakamoto;Ryosuke Nakao;Hideki Hirose;NanaIshii;Makoto Umeda
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第1期
- transformation;
- Bhas 42 cells;
- v-Ha-ras;
- tumor-initiator;
- tumor-promoter;
15.Replacement of Animals in Education in Gujarat, India

机译：印度古吉拉特邦教育中的动物替代
- 作者：Nick Jukes
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第1期
- Replacement;
- alternative;
- education;
- India;
- InterNICHE;
16.Skin Sensitization Study by Quantitative Structure-Activity Relationships (QSAR)

机译：通过定量构效关系（QSAR）进行皮肤敏化研究
- 作者：Kazuhiro Sato;Tomohiro Umemura;Tarou Tamura;Yukinori Kusaka;Kohji Aoyama;Atsushi Ueda;Kohichi Harada;Keiko Minamoto;Takemi Otsuki;Kunihiko Yamashita;Tatsuya Takeshita;Eiji Shibata;Kunio Dobashi;Satomi Kameo;Muneyuki Miyagawa;Masaaki Kaniwa;Yoko Endo;Kohtaro Yuta
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第3期
- skin sensitization;
- QSAR;
- animal study;
- occupational exposure limit;
17.In Vitro Embryotoxicity Test of Four Plasticizers by Embryonic Stem Cell Test (EST)

机译：胚胎干细胞测试（EST）对四种增塑剂的体外胚胎毒性测试
- 作者：Koichi Imai;Shoji Takeda;Kazuhiko Suese;Yoshihiro Momota;Naotaka Kishimoto;Michiko Nakatsuka;Shunji Kumabe;Yasutomo Iwai;Shinji Kusakawa;Akito Tanoue
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第1期
- EST;
- embryotoxicity;
- embryoid body;
- plasticizer;
18.Skin Sensitization Study by Quantitative Structure-Activity Relationships (QSAR)

机译：通过定量构效关系（QSAR）进行皮肤敏化研究
- 作者：Kazuhiro Sato;Tomohiro Umemura;Tarou Tamura;Yukinori Kusaka;Kohji Aoyama;Atsushi Ueda;Kohichi Harada;Keiko Minamoto;Takemi Otsuki;Kunihiko Yamashita;Tatsuya Takeshita;Eiji Shibata;Kunio Dobashi;Satomi Kameo;Muneyuki Miyagawa;Masaaki Kaniwa;Yoko Endo;Kohtaro Yuta
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第1期
- skin sensitization;
- QSAR;
- animal study;
- occupational exposure limit;
19.Animal Experiments and Alternatives: Time to Confront Truth and Uncertainty, and to Combine Idealism with Realism

机译：动物实验和替代方法：面对真理和不确定性，将唯心主义与现实主义相结合的时刻
- 作者：Michael Balls
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第1期
- alternatives;
- animal experiments;
- replacement;
- risk;
- toxicity testing;
20.Morphological Characterization of a Reconstructed, Cultured Human Epidermal Model (LabCyte EPI-MODEL) As an Alternative to in Vivo Models

机译：重建，培养的人类表皮模型（LabCyte EPI模型）的形态表征作为体内模型的替代
- 作者：Masakazu Katoh;Kentaro Kubo;Fumiyasu Hamajima;Takahiro Ogasawara;Ken-ichiro Hata
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第1期
- reconstructed human skin;
- morphology;
- epidermis;
21.Real-time Evaluation of Hemocompatible Materials by Human Platelets as an Alternative to Animal Experimentation

机译：人类血小板替代动物实验对血液相容性材料的实时评估
- 作者：Katsuko S Furukawa;Satoshi Seki;Yuki Hirano;Hanako Miki;Kazuyuki Mizuhara;Takashi Yamaiie;Tetsuya Tateishi;Takashi Ushida
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第2期
- human blood from bank;
- cone and plate-type rheometer;
- shear stress;
- small volume;
- hemocompatibility;
22.Cardiotoxicity of Anticancer Drug in Chick Embryos

机译：小鸡胚胎中抗癌药的心脏毒性
- 作者：Hiroyuki Miyazaki;Toshimi Iizuka;Motohiro Okayasu;Toshihiro Noda;Takenori Tamaki;Yuji Yoshiyama
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第3期
- cardiotoxicity;
- anticancer drug;
- arsenic trioxide;
- chick embryo;
- electrocardiogram;
23.Morphological Characterization of a Reconstructed, Cultured Human Epidermal Model (LabCyte EPI-MODEL) As an Alternative to in Vivo Models

机译：重建，培养的人类表皮模型（LabCyte EPI模型）的形态表征作为体内模型的替代
- 作者：Masakazu Katoh;Kentaro Kubo;Fumiyasu Hamajima;Takahiro Ogasawara;Ken-ichiro Hata
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第2期
- reconstructed human skin;
- morphology;
- epidermis;
24.In Vitro Embryotoxicity Test of Four Plasticizers by Embryonic Stem Cell Test (EST)

机译：胚胎干细胞测试（EST）对四种增塑剂的体外胚胎毒性测试
- 作者：Koichi Imai;Shoji Takeda;Kazuhiko Suese;Yoshihiro Momota;Naotaka Kishimoto;Michiko Nakatsuka;Shunji Kumabe;Yasutomo Iwai;Shinji Kusakawa;Akito Tanoue
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第3期
- EST;
- embryotoxicity;
- embryoid body;
- plasticizer;
25.Novel Experimental System as an Alternative to Animal Experiments to Study the Skin Permeation of Drugs

机译：新型实验系统可替代动物实验来研究药物的皮肤渗透
- 作者：Toshinobu Seki;Tatsuya Sashida;Shinji Oshima;Yuya Egawa;Hiroko Nakagawa;Osamu Hosoya;Kazuhiko Juni
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第2期
- skin absorption;
- microdialysis;
- artificial membrane;
- zero net flux;
- protein binding;
26.Novel Experimental System as an Alternative to Animal Experiments to Study the Skin Permeation of Drugs

机译：新型实验系统可替代动物实验来研究药物的皮肤渗透
- 作者：Toshinobu Seki;Tatsuya Sashida;Shinji Oshima;Yuya Egawa;Hiroko Nakagawa;Osamu Hosoya;Kazuhiko Juni
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第1期
- skin absorption;
- microdialysis;
- artificial membrane;
- zero net flux;
- protein binding;
27.Cardiotoxicity of Anticancer Drug in Chick Embryos

机译：小鸡胚胎中抗癌药的心脏毒性
- 作者：Hiroyuki Miyazaki;Toshimi lizuka;Motohiro Okayasu;Toshihiro Noda;Takenori Tamaki;Yuji Yoshiyama
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2009年第1期
- cardiotoxicity;
- anticancer drug;
- arsenic trioxide;
- chick embryo;
- electrocardiogram;
28.Peer to Peer Interaction Promotes Implementation of the Three Rs and Harmonization of Animal Care and Use Programs

机译：点对点互动促进了“三个R”的实施和动物护理与使用计划的协调
- 作者：Kathryn Bayne
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2010年第1期
- Three Rs;
- harmonization;
- laboratory animal;
- peer interaction;
29.Study of a Drug Interaction Involving the Permeation Process Using an Artificial Skin Model as an Alternative to Animal Skin

机译：使用人工皮肤模型替代动物皮肤的涉及渗透过程的药物相互作用的研究
- 作者：Shinji Oshima;Tatsuya Sashida;Yuya Egawa;Osamu Hosoya;Kazuhiko Juni;Toshinobu Seki
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2010年第2期
- skin absorption;
- drug interaction;
- artificial membrane;
- skin model;
- protein binding;
30.Contributor's Various Important Points of Scientific Basic Design for the Journal of Alternatives to Animal Testing and Experimentation

机译：《动物试验与替代品杂志》作者的科学基础设计的各个要点
- 作者：Koichi Imai
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2010年第3期
- publication;
- review system;
- AATEX;
31.News from NICEATM and ICCVAM

机译：NICEATM和ICCVAM的新闻
- 作者：William S. Stokes
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2010年第3期
- alternative test methods;
- validation;
- endocrine disruptors;
- vaccine testing;
- safety testing;
32.The Japanese Ring Study of a Human Cell Line Activation Test (h-CLAT) for Predicting Skin Sensitization Potential (5th Report): A Study for Evaluating Preservative Skin Sensitization Potential Using h-CLAT

机译：日本环研究人类细胞系激活测试（h-CLAT）预测皮肤敏化潜能（第5次报告）：使用h-CLAT评估防腐剂皮肤敏化潜能的研究
- 作者：Nanae Kosaka;Hiroyuki Inaba;Kenji Okamoto;Makoto Mizuno;Sakiko Sono;Yoshinao Kato;Masataka Kishi;Takao Ashikaga;Yuko Okamoto;Hirofumi Kuwahara;Tsuneaki Nakamura;Hitoshi Sakaguchi;Yasuo Ohno
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2010年第2期
- h-CLAT;
- skin sensitization;
- alternatives;
- THP-1;
- preservative;
33.A Study on the Dose Setting of Test Chemicals for the Promotion Assay in Bhas 42 Cell Transformation Assay

机译：Bhas 42细胞转化试验中用于促进试验的测试化学品剂量设定的研究
- 作者：Shoko Arai;Noriho Tanaka;Kiyoshi Sasaki;Ayako Sakai
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2010年第1期
- cell transformation assay;
- Bhas 42 cell;
- tumor promoter;
- dose setting;
- cytotoxicity;
34.Utilization of Reconstructed Cultured Human Skin Models as an Alternative Skin for Permeation Studies of Chemical Compounds

机译：重建培养的人类皮肤模型作为替代皮肤用于化学物质渗透研究的方法
- 作者：Satoshi Kano;Hiroaki Todo;Kenichi Sugie;Hidenori Fujimoto;Keiichi Nakada;Yoshihiro Tokudome;Fumie Hashimoto;Kenji Sugibayashi
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2010年第2期
- reconstructed human skin models;
- skin permeation;
- alternative membrane;
- skin corrosive/irritation;
35.Laboratory Animal Use in Great Britain in 2009

机译：2009年英国的实验动物使用
- 作者：Andrew Knight
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2010年第2期
- animal experiment;
- Great Britain;
- 3Rs;
- alternative;
- animal welfare;
36.Suitability of Synthetic Copolymer Membranes as a Human Skin Alternative for In Vitro Skin Permeation Testing

机译：合成共聚物膜作为人体皮肤替代品在体外皮肤渗透测试中的适用性
- 作者：Ryotaro Miki;Soichiro Kimura;Hideo Ueda;Takeshi Shimamura;Sachihiko Numajiri;Toshinobu Seki;Kazuhiko Juni;Hiromi Kitano;Yasunori Morimoto
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2010年第1期
- skin permeability;
- skin alternative;
- transdermal drug delivery system;
- copolymer membrane;
- artificial skin;
37.A Respiratory Sensitization Study by a New Quantitative Structure-Activity Relationships (QSAR)

机译：通过新的定量构效关系（QSAR）进行呼吸敏化研究
- 作者：Kazuhiro Sato;Tomohiro Umemura;Taro Tamura;Yukinori Kusaka;Toshiko Ido;Kohji Aoyama;Atsushi Ueda;Kohichi Harada;Keiko Minamoto;Takemi Otsuki;Kunihiko Yamashita;Tatsuya Takeshita;Eiji Shibata;Kunio Dobashi;Satomi Kameo;Muneyuki Miyagawa;Masaaki Kaniwa;Takahiko Yoshida;Tetsuhito Fukushima;Kohtaro Yuta
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2010年第3期
- respiratory sensitization;
- quantitative structure-activity relationships (QSAR);
- animal study;
38.Animal Experiments in Undergraduate Education at Dental Colleges and University Faculties of Dentistry in Japan

机译：日本牙科学院和大学牙科学院本科教育中的动物实验
- 作者：Koichi Imai
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2010年第2期
- dental college;
- dental school;
- animal experiment;
- Japan;
39.The Japanese Ring Study of a Human Cell Line Activation Test (h-CLAT) for Predicting Skin Sensitization Potential (6th Report): A Study for Evaluating Oxidative Hair Dye Sensitization Potential Using h-CLAT

机译：日本环研究人类细胞系激活测试（h-CLAT）预测皮肤敏化潜能（第6次报告）：使用h-CLAT评估氧化型染发剂敏化潜能的研究
- 作者：Nanae Kosaka;Hiroyuki Inaba;Kenji Okamoto;Makoto Mizuno;Sakiko Sono;Yoshinao Kato;Masataka Kishi;Takao Ashikaga;Yuko Okamoto;Hirofumi Kuwahara;Tsuneaki Nakamura;Hitoshi Sakaguchi;Yasuo Ohno
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2010年第2期
- h-CLAT;
- skin sensitization;
- alternatives;
- Bandrowski's base;
- hair dye;
40.The Japanese Ring Study of a Human Cell Line Activation Test (h-CLAT) for Predicting Skin Sensitization Potential (7**' Report): Evaluation of Volatile, Poorly Soluble Fragrance Materials

机译：一项针对人体细胞系激活测试（h-CLAT）的日本环研究，用于预测皮肤敏化潜能（7 **“报告）：挥发性，难溶性香料材料的评估
- 作者：Nanae Kosaka;Hiroyuki Inaba;Kenji Okamoto;Makoto Mizuno;Sakiko Sono;Yoshinao Kato;Masataka Kishi;Takao Ashikaga;Yuko Okamoto;Hirofumi Kuwahara;Tsuneaki Nakamura;Hitoshi Sakaguchi;Yasuo Ohno
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2010年第2期
- skin sensitization;
- alternative test;
- fragrance;
- h-CLAT;
41.Functional evaluation of the hepatocyte micropatterned chip

机译：肝细胞微模式芯片的功能评估
- 作者：Kohji Nakazawa;Yukiko Yoshiura;Yusuke Sakai
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
42.Study for the factors that influence the evaluation of subjective peel force of adhesive tapes

机译：影响胶带主观剥离力评估的因素研究
- 作者：Maki Shibuya;Kazuya Fukuhara;Masaki Uchida;Hideshi Natsume;Yasunori Morimoto
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
43.Development of a new in vitro skin sensitization assay using Reconstructed Human Epidermis (EpiSensA)

机译：使用重组人表皮（EpiSensA）开发新的体外皮肤致敏测定
- 作者：Saito Kazutoshi;Nukada Yuko;Takenouchi Osamu;Miyazawa Masaaki;Sakaguchi Hitoshi;Nishiyama Naohiro
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
44.Human Drug Transporter Gene-expressing Cells are Useful Alternatives to Predict Pharmacokinetics in Man

机译：表达人类药物转运蛋白基因的细胞是预测人体药代动力学的有用替代品
- 作者：Naohiko Anzai;Shin Wakui;Promsuk Jutabha;Tomoko Muto;Michinari Hayashi;Keitaro Hayashi;Mariko Domae;Kohsuke Uchida;Michael F. Wempe;Hitoshi Endou
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第2期
- drug transporters;
- transport substrates;
- drug-drug interaction;
- drug development;
- alternatives;
45.Development of myocardial toxicity test using cardiomyocytes derived from ES/iPS cells as an alternative to the cardiotoxic in vivo test - Analysis of chronotropic and inotropic actions -

机译：使用源自ES / iPS细胞的心肌细胞替代体外体内毒性试验，开发心肌毒性试验-变时性和变力作用的分析-
- 作者：Sumiko Kawai;Yasuhiro Takagi;Kyoko Shioya;Tsutomu Kurosawa
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
46.Development of in vitro and in silico alternative method for acute systemic toxicity in vivo

机译：体内和体外急性急性系统毒性计算机替代方法的发展
- 作者：Tomomi Atobe;Shigenobu Hagino;Masato Kitagaki;Hirokazu Kouzuki
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
47.A validation study on the 96-well method of Bhas 42 cell transformation assay

机译：Bhas 42细胞转化试验96孔方法的验证研究
- 作者：Ayako Sakai;Shoko Arai;Kiyoshi Sasaki;Dai Muramatsu;Nobuko Endou;Fukutaro Mizuhashi;Sawako Kasamoto;Miho Nagai;Maiko Takai;Masumi Asakura;Nobuhiko Tashiro;Nana Ishii;Shojiro Yamazaki;Makoto Umeda;Noriho Tanaka
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
48.Development of a well-of-the-well system-based embryo culture plate for the evaluation of embryo quality by photoluminescence imaging

机译：基于孔系统的胚胎培养板的开发，用于通过光致发光成像评估胚胎质量
- 作者：K. Komori;S. Fujii;K. Montagne;H. Nakamura;H. Kimura;T. Fujii;Y. Sakai
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
49.Fabrication of biomimetic tissues composed of cells of more than 2 types: A promising new prospect for biomedical studies

机译：由两种以上类型的细胞组成的仿生组织的制造：生物医学研究的新前景
- 作者：Jeong Ik Lee;Hyun Woo Kim;Su Jin Bae
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
50.In Vitro Embryotoxicity Test of Nanomaterials with ES cells

机译：ES细胞纳米材料的体外胚胎毒性测试
- 作者：Koichi Imai
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
51.Study on replacement of animal testing required in the former 'Standards to Approval of Hemodializer'

机译：替代以前的《除菌剂批准标准》中要求的动物试验的研究
- 作者：Yuji Fujita;Shinichi Kora
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
52.-Thoughts in animal life and responsibility of technician- With an experience of Eastern Japan Earthquake

机译：-关于动物生活的思考和对技术人员的责任-具有日本东部地震的经验
- 作者：Teruko SUETA
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
53.Establishment of new in vitro eye irritation test method using reconstructed human corneal epithelium, LabCyte CORNEA-MODEL

机译：重建的人角膜上皮LabCyte CORNEA-MODEL建立新的体外眼刺激试验方法
- 作者：Masakazu Katoh;Fumiyasu Hamajima;Takahiro Ogasawara;Ken-ichiro Hata
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
54.Quantitative prediction method of in vivo renal clearance of drugs using human kidney and expression system

机译：利用人肾脏和表达系统定量预测药物在体内肾脏清除率的方法
- 作者：Hiroyuki Kusuhara
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
55.The International Cooperation on Alternative Test Methods (ICATM) update

机译：国际替代试验方法合作组织（ICATM）更新
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
56.Cell culture on carbon nanotube thin films

机译：碳纳米管薄膜上的细胞培养
- 作者：Tsukasa Akasaka;Fumio Watari
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
57.Acetylcholine inhibits the hypoxia and hydrogen peroxide -induced reduction of connexin43 protein in rat cardiomyocytes.

机译：乙酰胆碱抑制低氧和过氧化氢诱导的大鼠心肌细胞中connexin43蛋白的减少。
- 作者：Hideto Ariumi
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
58.Alternatives to Animal Testing: Toward Reducing Uncertainty and Unintended Consequences

机译：动物试验的替代方法：减少不确定性和意外后果
- 作者：Michael Balls
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第3期
- animal experimentation;
- replacement alternatives;
- testing;
59.The Utility of the Peroxidase Peptide Reactivity Assay for the Identification of Skin Allergens

机译：过氧化物酶肽反应性测定在皮肤过敏原鉴定中的应用
- 作者：G. Frank Gerberick;John A. Troutman;Leslie M. Foertsch;Jean-Pierre Lepoittevin
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
60.Chemical list for the development of alternatives for skin irritation

机译：用于开发刺激皮肤的替代品的化学清单
- 作者：Yasuo Ohno;Masaharu Akita;Noriyasu Imai;Takashi Omori;Yuko Okamoto;Hidenobu Okumura;Yuki Kawano;Mariko Sugiyama;Shigenobu Hagino
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
61.Evaluation of Newly-Developed Qualitative Structure-Activity Relationships software

机译：新开发的定性结构-活动关系软件的评估
- 作者：Masahiro Haitsuka;Kunihiko Yamashita;Masatake Kudoh;Kohtaro Yuta;Kazuhiro Sato;Yukinori Kusaka
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
62.Three Dimensional Tissue Regeneration Using RWV Bioreaetor and Its In Vitro Evaluation

机译：使用RWV生物反应器进行三维组织再生及其体外评估
- 作者：Toshimasa UEMURA
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
63.Recent Research of Alternative Methods in Biotoxtech, Korea

机译：韩国生物毒素技术替代方法的最新研究
- 作者：Mi-Sook Jung;Mi-Ae Park;Heung-Mo Bae;Tae-Won Jeon;Seong-Jin Baek;Jong-Koo Kang
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
64.Establishment and application of predictive method for skin concentration of several compounds using skin permeation parameters

机译：皮肤渗透参数的几种化合物皮肤浓度预测方法的建立与应用
- 作者：Takeshi Oshizaka;Hiroaki Todo;Kenji Sugibayashi
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
65.Paramecium as a sensitive in vitro bioassay system for cytotoxicity of nanomaterials

机译：草履虫作为灵敏的体外生物测定系统对纳米材料的细胞毒性
- 作者：Nobuyuki Haga;Taiki Abe;Koichi Haneda
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
66.Study of in vitro skin irritation test targeted for sensitive skin

机译：针对敏感皮肤的体外皮肤刺激试验的研究
- 作者：Hidefumi Ikeda;Hideki Nishiura;Masakazu Katoh
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
67.Quantification of Bhas 42 cell transformation assay with hydrogen peroxide method

机译：过氧化氢法定量Bhas 42细胞转化测定
- 作者：Kiyoshi Sasaki;Dai Muramatsu;Shoko Arai;Nobuko Endou;Ayako Sakai;Shojiro Yamazaki;Makoto Umeda;Noriho Tanaka
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
68.Chemistry and Mechanism of SH-group Modifications Involved in Skin Sensitization

机译：皮肤敏化的SH基团修饰的化学和机理
- 作者：Yoshiharu Iwabuchi
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
69.Multi-Functional Hydrogel as Biomaterials

机译：多功能水凝胶作为生物材料
- 作者：Takayuki Kurokawa;Jian Ping Gong
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
70.A study of the eye irritation test using new immortalized human corneal epithelium

机译：新型永生化人角膜上皮刺激眼睛的实验研究
- 作者：Naoki Yamamoto
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
71.Basic study of an alternative test method of skin sensitization model using vitrigel chamber

机译：使用玻璃化凝胶腔的皮肤致敏模型替代测试方法的基础研究
- 作者：Tadashi Uchino;Toshiaki Takezawa;Kunihiko Yamashita;Hajime Kojima;Yoshiaki Ikarashi;Testuji Nishimura
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
72.Standardization for measurement about ear thickness of the pre-screen test on TG442A (LLNA:DA)

机译：在TG442A（LLNA：DA）上进行筛检前耳朵厚度测量的标准化
- 作者：Kunihiko Yamashita;Takashi Omori;Shinsuke Shinoda;Saori Hagiwara
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
73.Statistical prediction model for skin sensitization potential using an integrated dataset from h-CLAT, DPRA, and DEREK

机译：使用h-CLAT，DPRA和DEREK的集成数据集进行皮肤致敏潜力的统计预测模型
- 作者：Kenji Okamoto;Yuko Nukada;Masaaki Miyazawa;Hitoshi Sakaguch;Akihiko Takatsu
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
74.Development of a high-sensitive toxic assessment system in vitro using human artificial chromosome vector

机译：利用人类人工染色体载体开发高灵敏度毒性体外评估系统
- 作者：Tadashi Nishida;Yuki Yoshimura;Katsutaka Sasaki;Yoshihiro Nakajima;Rumiko Saito;Yasuhiro Kazuki;Shigeaki Nishii;Yoshihiro Ohmiya;Setsuya Aiba;Mitsuo Oshimura;Tetsuya Ohbayashi
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
75.Comparison of Several Reconstructed Cultured Human Skin Models by Microscopic Observation: Their Usefulness as an Alternative Membrane for Skin in Drug Permeation Experiments

机译：通过显微镜观察比较几种重建的培养的人类皮肤模型：它们在药物渗透实验中作为皮肤替代膜的有用性
- 作者：Satoshi Kano;Hiroaki Todo;Katsunon Furui;Kenichi Sugie;Yoshihiro Tokudome;Fumie Hashimoto;Hajime Kojima;Kenji Sugibayashi
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第2期
- reconstructed cultured human skin model;
- skin permeation;
- skin morphology;
- lamella layer;
76.Influence prediction of phthalate by the cultured human alveolar epithelial A549 cells and the numerical model

机译：人肺泡上皮细胞A549对邻苯二甲酸酯的影响预测及数值模型
- 作者：Kokoro Iwasawa;Genya Tanaka;Kikuo Komori;Takao Fujii;Kosaku Okuyama;Kenichi Hatanaka;Yoshiaki Sakoda;Toshiko Tanaka-Kagawa;Hideto Jinno;Yasuyuki Sakai
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
77.Skin sensitization study by a new qualitative structure-toxicity relationships (QSTR) approach: K-step Yard sampling (KY) methods

机译：通过新的定性结构-毒性关系（QSTR）方法进行的皮肤致敏研究：K步码取样（KY）方法
- 作者：Kazuhiro Sato;Kohtaro Yuta;Yukinori Kusaka
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
78.Study on alternative eye irritation test with novel immortalized human corneal epithelial cell line

机译：新型永生化人角膜上皮细胞系替代性眼刺激试验的研究
- 作者：Yoshinao Kato;Naoki Yamamoto;Hiromi Yamashita;Atsushi Sato;Hiroshi Mizutani;Satoru Nakata;Hajime Kojima
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
79.A new MAFF project 'Agri-health translational research project (Vitrigel)'

机译：MAFF的新项目“农业健康转化研究项目（Vitrigel）”
- 作者：Toshiaki Takezawa
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
80.A genotoxicity test based on p53R2 gene expression in human cells. (NESMAGET, Part10) : Investigation the applicability of the test in TK6 cells

机译：基于人细胞中p53R2基因表达的遗传毒性测试。（NESMAGET，第10部分）：研究该测试在TK6细胞中的适用性
- 作者：Taisei Mizota;Katsutoshi Ohno;Mina Ito;Toshihiro Yamada
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
81.Refinement of LabCyte EPI-MODEL24 Skin Irritation Test Method for Adaptation to the Requirements of OECD Test Guideline 439

机译：改进LabCyte EPI-MODEL24皮肤刺激性测试方法以适应OECD测试准则439的要求
- 作者：Masakazu Katoh;Kenichiro Hata
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第3期
- reconstructed human epidermal model;
- skin irritation;
- OECD test guideline 439;
82.Development of the in vitro photo-sensitization assay by detecting changes of cell surface thiols and amines

机译：通过检测细胞表面硫醇和胺类的变化开发体外光敏测定
- 作者：Shiho Oeda;Morihiko Hirota;Hirokazu Kouzuki;Setsuya Aiba;Yoshiki Tokura
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
83.An inter-laboratory pre-validation study of the novel embryonic stem cell tests (Handl-EST and Cmyal-EST) for developmental toxicity

机译：实验室间针对新型胚胎干细胞试验（Handl-EST和Cmyal-EST）的发育前验证研究
- 作者：Noriyuki Suzuki;Naoteru Koseki;Yutaka Kimura;Setsuya Aiba;Tomoyasu Toyoizumi;Mika Watanabe;Ryo Ohta;Koichi Saito
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
84.Novel efficacy evaluations of cosmetics with reconstructed human epidermis models

机译：重建人类表皮模型对化妆品的新型功效评估
- 作者：Daisuke Yoshida;Yukiko Izutsu;Keisuke Tanaka;Nobuyuki Uiiie;Daiki Kyotani;Jinhua Li
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
85.Advantage of a human corneal epithelium model reconstructed in a collagen vitrigel membrane chamber: A novel approach to extrapolate eye irritation from the time dependent profile of transepithelial electrical resistance after exposing chemicals

机译：在胶原玻璃体凝胶膜腔中重建人角膜上皮模型的优势：从暴露化学物质后经上皮电阻随时间变化的轮廓推断眼睛刺激的新方法
- 作者：Hiroyuki Yamaguchi;Hajime Kojima;Toshiaki Takezawa
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
86.Controlling the contractile myotubes by the flexible organic electrode

机译：通过柔性有机电极控制收缩肌管
- 作者：Y. Ido;D. Takahashi;R. Suziki;M. Sasaki;K. Nagamine;T. Miyake;M. Nishizawa
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
87.An attempt to improve the accuracy of IL-8 Luc assay

机译：尝试提高IL-8 Luc检测的准确性
- 作者：Yutaka Kimura;Toshiya Takahashi;Rumiko Saito;Yoshihiro Nakajima;Yoshihiro Ohmiya;Kenshi Yamasaki;Setsuya Aiba
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
88.Additonal multisite study of reconstructed human epidermis, LabCyte EPI-MODEL24 skin irritation test.

机译：重建人表皮的其他多点研究，LabCyte EPI-MODEL 24皮肤刺激性试验。
- 作者：Shinoda S;Hagiwara S;Yamagichi Y;Nakamura A;Kasahara T;Shibai A;Katoh M;Kojima H
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
89.The Evolution of Skin Sensitization Test Methods and their Utility in Quantitative Risk Assessment

机译：皮肤敏化测试方法的演变及其在定量风险评估中的效用
- 作者：G. Frank Gerberick;Cindy A. Ryan;Carsten Goebel;Petra S. Kern
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
90.Recent Progress in the Development of Organ-on-a-Chip Devices for Drug Discovery

机译：用于药物发现的片上器官装置开发的最新进展
- 作者：Hirokazu Kaji
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
91.The human Cell Line Activation Test (h-CLAT) based on alteration of cell surface markers expression by developed and applied in Japan

机译：在日本开发并应用了基于细胞表面标志物表达变化的人类细胞系激活测试（h-CLAT）
- 作者：H. Sakaguchi;T. Ashikaga;Y. Nukada;S. Sono;M. Miyazawa;H. Sasa;N. Nishiyama
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
92.Usefulness of liposome membrane as a tool to evaluate the enhancing of electroporation on the skin permeation of drugs

机译：脂质体膜作为评估药物对皮肤渗透的电穿孔增强作用的工具
- 作者：Sayaka Nishio;Hiroaki Todo;Kenji Sugibayashi
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
93.The Japanese Center for the Validation of Alternative Methods (JaCVAM) update

机译：日本替代方法验证中心（JaCVAM）更新
- 作者：Hajime Kojima
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
94.Definition of the applicability domain of the STE test based on the background review analysis

机译：基于背景审查分析的STE测试适用范围的定义
- 作者：Kazuhiko Hayashi;Yuko Nukada;Takayuki Abo;Hitoshi Sakaguchi;Naohiro Nishiyama
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
95.Analysis of metal immunotoxicity using T cell-derived Jurkat reporter cell line, #2H4

机译：使用源自T细胞的Jurkat报告基因细胞＃2H4分析金属免疫毒性
- 作者：Rumiko Saito;Satoshi Hirakawa;Hiroshi Ohara;Makoto Yasuda;Tomomi Yamazaki;Shigeaki Nishii;Setsuya Aiba
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
96.Testing strategy for skin sensitization by using in vitro tests andin silico system

机译：使用体外测试和计算机系统对皮肤致敏性的测试策略
- 作者：Yuko Nukada;Hiroki Sano;Masaaki Miyazawa;Kazutoshi Saito;Hitoshi Sakaguchi;Naohiro Nishiyama
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
97.Approach of Shiseido for Safety Assessment in silico

机译：资生堂计算机安全评估方法
- 作者：Hirokazu Kouzuki
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
98.The Reproducibility of the Validated EPI-200 Skin Irritation Test (EPI-200 SIT) in Japan

机译：在日本经过验证的EPI-200皮肤刺激性测试（EPI-200 SIT）的可重复性
- 作者：Yuki Handa;Fumi Ichinose;Helena Kandarova;Hiroshi Yanase
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
99.The optimization for preparing the lymph node cell suspension in LLNA BrdU-ELISA

机译：LLNA BrdU-ELISA中制备淋巴结细胞悬液的优化
- 作者：Yuko Maruyama;Atsuko Yuasa;Takanori Hioki;Toshihiko Kasahara;Hajime Kojima
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期
100.Education program on animal-experiment ethics based on international guidelines

机译：基于国际准则的动物实验伦理教育计划
- 作者：Shigeo Ito
- 期刊名称：《Alternatives to Animal Testing and Experimentation》 | 2011年第1期

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