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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Dietary folate, riboflavin, vitamin B-6, and vitamin B-12 and depressive symptoms in early adolescence: the Ryukyus Child Health Study.
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Dietary folate, riboflavin, vitamin B-6, and vitamin B-12 and depressive symptoms in early adolescence: the Ryukyus Child Health Study.

机译：膳食叶酸，核黄素，维生素B-6和维生素B-12以及青春期早期的抑郁症状：《琉球儿童健康研究》。

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OBJECTIVE: To examine the association between dietary folate, riboflavin, vitamin B-6, and vitamin B-12 and depressive symptoms in a group of adolescents. METHODS: This cross-sectional study, conducted in all public junior high schools in Naha City and Nago City, Okinawa, Japan, included 3,067 boys and 3,450 girls aged 12 years to 15 years (52.3% of eligible sample). Dietary intake was assessed using a validated, self-administered diet history questionnaire. Depressive symptoms were defined as present when participants had a Center for Epidemiologic Studies Depression Scale score of >/=16. RESULTS: The prevalence of depressive symptoms was 22.5% for boys and 31.2% for girls. Folate intake was inversely associated with depressive symptoms in both boys (adjusted odds ratio (OR) [95% confidence interval (CI)] in the highest (compared with the lowest) quintile, 0.60 [0.45, 0.79]; p for trend = .002) and girls (OR [95% CI], 0.61 [0.48, 0.77]; p for trend = <.001). Vitamin B-6 intake was inversely associated with depressive symptoms in both boys (OR [95% CI], 0.73 [0.54, 0.98]; p for trend = .02) and girls (OR [95% CI], 0.72 [0.56, 0.92]; p for trend = .002). Riboflavin intake was inversely associated with depressive symptoms in girls (OR [95% CI], 0.85 [0.67, 1.08]; p for trend = .03), but not in boys. No clear association was seen between vitamin B-12 intake and depressive symptoms in either sex. CONCLUSIONS: This study suggests that higher intake of dietary B vitamins, particularly folate and vitamin B-6, is independently associated with a lower prevalence of depressive symptoms in early adolescence.
机译：目的：研究饮食中叶酸，核黄素，维生素B-6和维生素B-12与一组青少年的抑郁症状之间的关系。方法：这项横断面研究在日本冲绳那霸市和名护市的所有公立初中进行，包括年龄在12岁至15岁之间的3,067名男孩和3,450名女孩（占合格样本的52.3％）。使用经过验证的自我饮食史调查表评估饮食摄入量。当参与者的流行病学研究中心抑郁量表得分大于/ = 16时，就会出现抑郁症状。结果：男孩的抑郁症状患病率为22.5％，女孩的患病率为31.2％。叶酸摄入与两个男孩的抑郁症状呈负相关（校正后的优势比（OR）[95％置信区间（CI）]），最高的五分位数为0.60 [0.45，0.79];趋势的p =。 002）和女孩（OR [95％CI]，0.61 [0.48，0.77];趋势p = <.001）。男孩（OR [95％CI]，0.73 [0.54，0.98];趋势p = .02）和女孩（OR [95％CI]，0.72 [0.56， 0.92];趋势的p = .002）。女生服用核黄素与抑郁症状呈负相关（OR [95％CI]，0.85 [0.67，1.08];趋势p = .03），而男孩则没有。两种性别的维生素B-12摄入量与抑郁症状之间均未见明确关联。结论：这项研究表明，饮食中维生素B的摄入量较高，尤其是叶酸和维生素B-6，与青春期早期抑郁症状的发生率较低独立相关。

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