Cystatin C-Based eGFR Is a Superior Prognostic Parameter to Creatinine-Based eGFR in Post-Endovascular Therapy Peripheral Artery Disease Patients

Otaki Yoichiro; Takahashi Hiroki; Watanabe Tetsu; Yamaura Gensai; Funayama Akira; Arimoto Takanori; Shishido Tetsuro; Miyamoto Takuya; Kubota Isao

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Cystatin C-Based eGFR Is a Superior Prognostic Parameter to Creatinine-Based eGFR in Post-Endovascular Therapy Peripheral Artery Disease Patients

机译：基于胱抑素C的eGFR在血管内治疗后外周动脉疾病患者中优于基于肌酐的eGFR的预后参数

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Background: Kidney dysfunction is reportedly associated with adverse outcome in patients with peripheral artery disease (PAD). Estimated glomerular filtration rate (eGFR), a recently popularized index for assessing kidney function, is calculated using serum creatinine or cystatin C. Compared with creatinine-based eGFR (eGFRcr), cystatin C-based eGFR (eGFRcys) is less affected by age, gender, and muscle mass. We hypothesized that eGFRcys is a feasible prognostic biomarker despite muscle sarcopenia in patients with PAD.

机译：背景：据报道，肾功能不全与外周动脉疾病（PAD）患者的不良结局有关。估计的肾小球滤过率（eGFR）是一种最近流行的评估肾功能的指标，是使用血清肌酐或半胱氨酸蛋白酶抑制剂C计算的。与基于肌酸酐的eGFR（eGFRcr）相比，基于胱抑素C的eGFR（eGFRcys）受年龄的影响较小，性别和肌肉质量。我们假设eGFRcys是一种可行的预后生物标志物，尽管PAD患者存在肌肉少肌症。

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《Circulation journal》 |2015年第11期|共8页
作者
Otaki Yoichiro; Takahashi Hiroki; Watanabe Tetsu; Yamaura Gensai; Funayama Akira; Arimoto Takanori; Shishido Tetsuro; Miyamoto Takuya; Kubota Isao;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
Creatinine-based eGFR; Cystatin C-based eGFR; Muscle sarcopenia; Peripheral artery disease;

机译：基于肌酐的eGFR;基于胱抑素C的eGFR;肌肉少肌症;周围动脉疾病;

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1. Cystatin C-Based eGFR Is a Superior Prognostic Parameter to Creatinine-Based eGFR in Post-Endovascular Therapy Peripheral Artery Disease Patients [J] . Otaki Yoichiro, Takahashi Hiroki, Watanabe Tetsu, Circulation journal . 2015,第11期

机译：基于胱抑素C的eGFR在血管内治疗后外周动脉疾病患者中优于基于肌酐的eGFR的预后参数
2. Cystatin C-Based eGFR Is a Superior Prognostic Parameter to Creatinine-Based eGFR in Post-Endovascular Therapy Peripheral Artery Disease Patients [J] . Yoichiro Otaki, Hiroki Takahashi, Tetsu Watanabe, Circulation journal . 2015,第11期

机译：基于胱抑素C的eGFR是血管内治疗后外周动脉疾病患者优于基于肌酐的eGFR的预后参数
3. Cystatin C-Based eGFR Is a Superior Prognostic Parameter to Creatinine-Based eGFR in Post-Endovascular Therapy Peripheral Artery Disease Patients [J] . Yoichiro Otaki, Hiroki Takahashi, Tetsu Watanabe, Circulation journal . 2015,第11期

机译：基于胱抑素C的eGFR是血管内治疗后外周动脉疾病患者优于基于肌酐的eGFR的预后参数
4. Association between tumor heterogeneity and progression-free survival in non-small cell lung cancer patients with EGFR mutations undergoing tyrosine kinase inhibitors therapy [C] . Jiangdian Song, Di Dong, Yanqi Huang, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2016

机译：接受酪氨酸激酶抑制剂治疗的EGFR突变非小细胞肺癌患者肿瘤异质性与无进展生存的关系
5. Guideline-Directed Statin Therapy in Patients with New or Worsening Symptoms of Peripheral Artery Disease [D] . Khariton, Yevgeniy. 2018

机译：患有周围性动脉疾病新症状或恶化症状的患者的指导性他汀类药物治疗
6. Associations between cystatin C-based eGFR ambulatory blood pressure parameters and in-clinic vs. ambulatory blood pressure agreement in older community-living adults [O] . Tyler B. Woodell, Jan M. Hughes-Austin, Tiffany V. Tran, -1

机译：老年社区居民中基于胱抑素C的eGFR动态血压参数与门诊血压与动态血压之间的关联
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Cystatin C-Based eGFR Is a Superior Prognostic Parameter to Creatinine-Based eGFR in Post-Endovascular Therapy Peripheral Artery Disease Patients

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