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Radiographic Incidence of Spinal Osteopathologies in Captive Rhesus Monkeys (Macaca mulatta)

机译:圈养恒河猴(猕猴)脊柱骨病理学的放射学发生率

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摘要

Degenerative spinal disease is a leading cause of chronic disability both in humans and animals. Although widely seen as a normal occurrence of aging, degenerative spinal disease can be caused by various genetic, iatrogenic, inflammatory, and congenital factors. The objective of this study was to characterize the degenerative spine-related diseases and the age at onset in a random subpopulation of 20 captive rhesus monkeys (Macaca mulatta; male, 13; female, 7; age: range, 4 to 27 y; median, 18.5 y). Spinal radiographic evaluation (left lateral, right lateral, and ventrodorsal views) of the spinal column (C1 to S1) was performed, and spinal degenerative disease was scored. The incidence of osteopathology was higher in the 14- to 18-y-old group, but incidence did not differ according to sex. In the studied population, degenerative changes were present in monkeys as young as 9 y of age.
机译:退行性脊柱疾病是人类和动物慢性残疾的主要原因。尽管广泛认为衰老是正常现象,但退行性脊柱疾病可以由多种遗传,医源性,炎性和先天性因素引起。这项研究的目的是在20只圈养恒河猴的随机亚群中鉴定退化性脊柱相关疾病和发病年龄(猕猴;雄性,13;雌性,7;年龄:4至27岁;中位,18.5年)。进行了脊柱(C1至S1)的脊柱X光检查(左侧,右侧和腹侧视图),并对脊柱退行性疾病评分。 14至18岁组的骨病理学发病率较高,但发病率并未因性别而异。在所研究的种群中,在9岁以下的猴子中出现了退化性变化。

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