Leucophyllidine, a Cytotoxic Bisindole Alkaloid Constituted From the Union of an Eburnan and a New Vinylquinoline Alkaloid

Gan CY; Robinson WT; Etoh T; Hayashi M; Komiyama K; Kam TS

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Leucophyllidine, a Cytotoxic Bisindole Alkaloid Constituted From the Union of an Eburnan and a New Vinylquinoline Alkaloid

机译：亮叶绿素，一种细胞毒性的双吲哚生物碱，由一种荚burn和新的乙烯基喹啉生物碱组成

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A cytotoxic bisindole alkaloid possessing an unprecedented structure constituted from the union of an eburnan half and a novel vinylquinoline alkaloid has been isolated from Leuconotis griffithii. The structure was established by analysis of the spectroscopic data and confirmed by X-ray diffraction analysis. A possible biogenetic pathway to the novel quinolinic coupling partner Is presented from an Aspidosperma precursor.

机译：具有细胞毒性的双吲哚生物碱具有前所未有的结构，该结构由荚burn半部分和新的乙烯基喹啉生物碱的结合体构成，该生物碱已从Leuconotis griffithii中分离出来。通过分析光谱数据确定结构，并通过X射线衍射分析确认。从曲霉前体中提出了通往新型喹啉偶合体的可能的生物遗传途径。

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《Organic letters》 |2009年第17期|共4页
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Gan CY; Robinson WT; Etoh T; Hayashi M; Komiyama K; Kam TS;
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1. Leucophyllidine, a Cytotoxic Bisindole Alkaloid Constituted From the Union of an Eburnan and a New Vinylquinoline Alkaloid [J] . Gan CY, Robinson WT, Etoh T, Organic letters . 2009,第17期

机译：亮叶绿素，一种细胞毒性的双吲哚生物碱，由一种荚burn和新的乙烯基喹啉生物碱组成
2. Bipleiophylline, an unprecedented cytotoxic bisindole alkaloid constituted from the bridging of two indole moieties by an aromatic spacer unit [J] . Kam TS, Tan SJ, Ng SW, Organic letters . 2008,第17期

机译：Bipleiophylline，一种前所未有的细胞毒性双吲哚生物碱，由两个吲哚部分通过一个芳香族间隔单元桥接而成
3. Ibogan, Tacaman, and Cytotoxic Bisindole Alkaloids from Tabernaemontana. Cononusine, an Iboga Alkaloid with Unusual Incorporation of a Pyrrolidone Moiety [J] . Lim Kuan-Hon, Raja Vijay J., Bradshaw Tracey D., Journal of natural products . 2015,第5期

机译：伊波根（Ibogan），塔卡曼（Tacaman）和Tabernaemontana的细胞毒性双吲哚生物碱。 Cononusine，一种不寻常掺入吡咯烷酮部分的Iboga生物碱
4. BfR Risk Assessment of Alkaloids as Ingredients and Contaminants of Food: Quinine, Opium Alkaloids, and Senecio Pyrrolizidine Alkaloids [C] . Birgit Dusemund, Klaus-Erich Appel, Alfonso Lampen Symposium on Risk Assessment of Phytochemicals in Food: Novel Approaches . 2010

机译：BFR风险评估生物碱作为食品的成分和污染物：奎宁，鸦片生物碱和肠染料吡咯氨酸生物碱
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6. A Fluorinated Analogue of Marine Bisindole Alkaloid 22-Bis(6-bromo-1 [O] . Raffaella Campana, Gianmarco Mangiaterra, Mattia Tiboni, 2020

机译：海岛基吲哚生物碱22-BIS的氟化类似物（6-溴-1
7. Ibogan, Aspidosperman, Vincamine, and Bisindole Alkaloids from a Malayan Tabernaemontana corymbosa: Iboga Alkaloids with C20 Substitution [O] . -1

机译：来自Malayan Tabernaemonterana Corymbosa的伊博尔曼，阿斯帕哌芒，vincamine和Bisindole生物碱：Iboga生物碱用C20替换

Leucophyllidine, a Cytotoxic Bisindole Alkaloid Constituted From the Union of an Eburnan and a New Vinylquinoline Alkaloid

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