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首页> 外文期刊>Cornea >Central Corneal Mechanical Sensitivity in Pseudoexfoliation Syndrome.
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Central Corneal Mechanical Sensitivity in Pseudoexfoliation Syndrome.

机译：假性剥脱综合征的中央角膜机械敏感性。

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PURPOSE:: Corneal involvement and disturbances of the tear film have been reported in pseudoexfoliation syndrome (PEX). Tear film deficiencies are correlated with changes in corneal sensitivity. The present study aims at evaluating central corneal mechanical sensitivity (CCMS) in PEX. METHODS:: Patients with unilateral or bilateral PEX findings constituted the study group (SG). Age- and gender-matched patients without PEX in either eye constituted the control group (CG). Patients with conditions affecting corneal sensitivity were excluded. CCMS and central corneal thickness (CCT) were measured (using a Cochet-Bonnet esthesiometer and an ultrasonic pachymeter, respectively). Schirmer (ST) and break-up time (BUT) tests were also performed. RESULTS:: The SG included 40 patients (24 male, 60%). The CG included 38 patients (25 male, 65.78%). ST scores were significantly lower in the SG compared with the CG (11.45 +/- 2.52 mm and 14.27 +/- 1.18 mm, respectively, P = 0.04). BUT scores were also significantly lower in the SG compared with the CG (7.64 +/- 2.37 mm and 12.43 +/- 3.14 mm, respectively, P = 0.03). CCMS was significantly (P = 0.02) reduced in the SG compared with CG (4.54 +/- 0.23 cm and 5.73 +/- 0.44 cm, respectively). Differences in CCT between the SG and the CG were not statistically significant. CONCLUSIONS:: The decrease in CCMS in PEX eyes may be related to decreased BUT and ST scores in PEX, as previously described. However, a direct involvement of sensory nerves may also participate. The reduction in CCMS may have implications for the clinical management of PEX patients.
机译：目的：在假性剥脱综合征（PEX）中已报道角膜累及泪膜。泪膜缺陷与角膜敏感性的变化有关。本研究旨在评估PEX中的中央角膜机械敏感性（CCMS）。方法：单侧或双侧PEX发现的患者组成研究组（SG）。年龄和性别匹配的两只眼睛都没有PEX的患者构成了对照组（CG）。排除影响角膜敏感性的患者。测量了CCMS和角膜中央厚度（CCT）（分别使用Cochet-Bonnet美容仪和超声测厚仪）。还进行了Schirmer（ST）和分手时间（BUT）测试。结果：SG包括40例患者（24例男性，60％）。 CG包括38例患者（25例男性，65.78％）。与CG相比，SG的ST评分明显更低（分别为11.45 +/- 2.52 mm和14.27 +/- 1.18 mm，P = 0.04）。与CG相比，SG的BUT评分也显着降低（分别为7.64 +/- 2.37毫米和12.43 +/- 3.14毫米，P = 0.03）。与CG相比，SG的CCMS显着降低（P = 0.02）（分别为4.54 +/- 0.23 cm和5.73 +/- 0.44 cm）。 SG和CG之间的CCT差异无统计学意义。结论：如前所述，PEX眼中CCMS的降低可能与PEX中BUT和ST得分的降低有关。但是，感觉神经的直接参与也可能参与。 CCMS的降低可能对PEX患者的临床管理有影响。

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