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HIC-net: A deep convolutional neural network model for classification of histopathological breast images

机译:HIC-NET:组织病理乳腺图像分类的深度卷积神经网络模型

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In this study, a convolutional neural network (CNN) model is presented to automatically identify cancerous areas on whole-slide histopathological images (WSI). The proposed WSI classification network (HIC-net) architecture performs window-based classification by dividing the WSI into a certain plane. In our method, an effective pre-processing step has been added for WSI for better predictability of image parts and faster training. A large dataset containing 30,656 images is used for the evaluation of the HIC-net algorithm. Of these images, 23,040 are used for training, 2560 are used for validation and 5056 are used for testing. HIC-net has more successful results than other state-of-art CNN algorithms with AUC score of 97.7%. If we evaluate the classification results of HIC-net using softmax function, HIC-net success rates have 96.71% sensitivity, 95.7% specificity, 96.21% accuracy, and are more successful than other state-of-the-art techniques which are used in cancer research. (C) 2019 Elsevier Ltd. All rights reserved.
机译:在该研究中,提出了一种卷积神经网络(CNN)模型,以自动识别全载组织病理学图像(WSI)上的癌症区域。所提出的WSI分类网络(HIC-Net)架构通过将WSI划分为特定平面来执行基于窗口的分类。在我们的方法中,为WSI添加了有效的预处理步骤,以便更好地预测图像部件和更快的训练。包含30,656个图像的大型数据集用于评估HIC-Net算法。在这些图像中,23,040用于训练,使用2560用于验证,5056用于测试。 HIC-Net具有比其他最先进的CNN算法更成功的结果,AUC分数为97.7%。如果我们使用Softmax函数评估HIC-Net的分类结果,HIC-Net成功率具有96.71%的灵敏度,特异性为95.7%,精度为96.21%,比其他最先进的技术更成功癌症研究。 (c)2019年elestvier有限公司保留所有权利。

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