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首页> 外文期刊>Cornea >Corneal Neurotization With a GreatAuricuIar Nerve Graft: Effective Reinnervation Demonstrated by In Vivo Confocal Microscopy
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Corneal Neurotization With a GreatAuricuIar Nerve Graft: Effective Reinnervation Demonstrated by In Vivo Confocal Microscopy

机译：角膜神经化与伟大的神经移植物：体内共聚焦显微镜证明的有效重试剂

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Purpose: We describe the first case of minimally invasive corneal neurotization with the great auricular nerve (GAN) to treat unilateral neurotrophic keratopathy. We assessed corneal sensation and reinnervation by esthesiometry and confocal microscopy over 12 months of follow-up, and we provide a detailed description of the surgical technique.Methods: Corneal neurotization was successfully achieved with the ipsilateral GAN in a 58-year-old woman. Cochet-Bonnet esthesiometry and in vivo confocal microscopy were performed before and after corneal neurotization, to monitor the recovery of corneal sensation and corneal reinnervation by subbasai nerve fibers.Results： Neurotrophic keratopathy was a complication of the surgical treatment of meningioma. Before surgery, the patient had no corneal sensation or corneal innervation. Six months after surgery, confocal microscopy confirmed regrowth of a large number of nerve fibers in the subepithelial space of the cornea. Nine months after surgery, a central esthesiometry score of 10-mm was attained.Conclusions： Corneal neurotization leads to reinnervation of the cornea and recovery of ocular sensation in adults. The GAN is suitable for use in corneal neurotization because of its anatomical proximity and the low level of associated morbidity. Confocal microscopy demonstrated the occurrence of corneal reinnervation, which preceded the recovery of corneal sensation.
机译：目的：我们描述了第一种用大耳穴神经（GaN）微创角膜神经化的案例，以治疗单侧神经营养的角病。我们评估了estheri测量的角膜感觉和重新转化，并在12个月的随访中得到了共聚焦显微镜，我们提供了对手术技术的详细描述。方法：角膜神经化在一个58岁的女性中成功实现了Ipsilatalal GaN。 Cochet-Bonnet estheriofortry和体内共聚焦显微镜检查在角膜神经化之前和之后进行，以监测次息神经纤维的角膜感觉和角膜再现的恢复。结果：神经营养的角病是脑膜瘤外科治疗的复杂性。在手术前，患者没有角膜感觉或角膜原理。手术后六个月，共聚焦显微镜证实了角膜上耻骨上的大量神经纤维的再生。手术后九个月，达到10毫米的中央estherioforry得分。结论：角膜神经化导致角膜的重新成因和成人中眼睛感觉的回收。 GaN适用于角膜神经调节，因为其解剖学接近和相关的发病率的低水平。共聚焦显微镜证明了角膜再现的发生，其特征在于恢复角膜感觉。

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