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Longitudinal segmentation of age-related white matter hyperintensities

机译:年龄相关的白质超萎缩的纵向分割

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摘要

Although white matter hyperintensities evolve in the course of ageing, few solutions exist to consider the lesion segmentation problem longitudinally. Based on an existing automatic lesion segmentation algorithm, a longitudinal extension is proposed. For evaluation purposes, a longitudinal lesion simulator is created allowing for the comparison between the longitudinal and the cross-sectional version in various situations of lesion load progression. Finally, applied to clinical data, the proposed framework demonstrates an increased robustness compared to available cross-sectional methods and findings are aligned with previously reported clinical patterns. (C) 2017 The Author(s). Published by Elsevier B.V.
机译:虽然白质高势率在老化过程中演变,但很少存在纵向地考虑病变分割问题。 基于现有的自动损伤分段算法,提出了纵向延伸。 为了评估目的,产生纵向病变模拟器,允许在病变负荷进展的各种情况下纵向和横截面形式之间的比较。 最后,应用于临床数据,所提出的框架与可用的横截面方法相比,鲁棒性增加,结果与先前报道的临床模式对齐。 (c)2017年作者。 elsevier b.v出版。

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