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首页> 外文期刊>American journal on intellectual and developmental disabilities: AJIDD >Biobehavioral Indicators of Social Fear in Young Children With Fragile X Syndrome
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Biobehavioral Indicators of Social Fear in Young Children With Fragile X Syndrome

机译：脆性X综合征幼儿社会恐惧的生物行为指标

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Anxiety is among the most impairing conditions associated with Fragile X syndrome (FXS) and is putatively linked to atypical physiological arousal. However, few studies have examined this association in young children with FXS. The authors examined whether patterns of arousal and behavior during an experimental stranger approach paradigm differ between a cross-sectional sample of 21 young children with FXS and 19 controls (12- 58 months old). Groups did not differ in mean levels of behavioral fear. Unlike the control group, however, the FXS group demonstrated increased facial fear at older ages, as well as age-dependent changes in associations between heart activity and distress vocalizations. These findings may inform theoretical models of anxiety etiology in FXS and early detection efforts.
机译：焦虑是与脆性X综合征（FXS）相关的最严重的疾病之一，并且被认为与非典型的生理唤醒有关。但是，很少有研究检查与FXS幼儿相关的这种关系。作者检查了21名FXS幼儿与19名对照（12-58个月大）的横断面样本之间的实验性陌生人进近范例中的唤醒方式和行为方式是否不同。各组在行为恐惧的平均水平上没有差异。但是，与对照组不同，FXS组在老年人中表现出面部恐惧感增加，并且在心脏活动和遇险声音之间的年龄相关性改变。这些发现可能会为FXS中的焦虑病因学理论模型和早期发现工作提供参考。

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