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Bioactive milk proteins and peptides: from science to functional applications.

机译:生物活性乳蛋白和多肽:从科学到功能应用。

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Milk proteins are known for their high nutritive value and diverse functional properties. Beyond these functions, milk proteins have attracted growing scientific and commercial interest as a source of biologically active molecules. Such proteins are found both in casein and whey protein fractions and can be enriched and purified industrially. The best characterised whey-based bioactive proteins include immunoglobulins, lactoferrin, lactoperoxidase and growth factors. The native milk proteins exhibit a wide range of biological activities that influence the digestive function, metabolic responses to absorbed nutrients, growth and development of organs and disease resistance. Whey-derived proteins, in particular, have proven beneficial in reduction of the risks of many chronic human diseases reflected by the metabolic syndrome. To this end, commercial applications are now being developed extensively. Other applications include preservation of foodstuffs and prevention of infectious diseases in humans and domestic animals. Over the past decade, a great number of peptides with specific bioactivities have been identified in major milk proteins. Such peptides can be liberated during gastrointestinal digestion or fermentation of milk by starter cultures. The efficacy of a few peptides has been established in animal and human studies and a number of commercial products have been launched on global markets. The great potential of bioactive milk peptides in promotion of human health has been realised and more commercial products are envisaged.
机译:牛奶蛋白以其高营养价值和多种功能特性而闻名。除这些功能外,牛奶蛋白作为生物活性分子的来源已引起越来越多的科学和商业兴趣。在酪蛋白和乳清蛋白级分中均发现了此类蛋白,并且可以在工业上进行富集和纯化。最具特色的乳清基生物活性蛋白包括免疫球蛋白,乳铁蛋白,乳过氧化物酶和生长因子。天然乳蛋白具有广泛的生物学活性,可影响消化功能,对吸收养分的代谢反应,器官的生长和发育以及抗病性。尤其是,乳清蛋白已被证明可降低代谢综合征所反映的许多慢性人类疾病的风险。为此,目前正在广泛地开发商业应用。其他应用包括食品的保存和预防人类和家畜的传染病。在过去的十年中,在主要的乳蛋白中已经鉴定出许多具有特定生物活性的肽。这类肽可以通过发酵剂在胃肠道消化或牛奶发酵过程中释放出来。在动物和人类研究中已经确定了几种肽的功效,并且已经在全球市场上推出了许多商业产品。已经认识到生物活性乳肽在促进人类健康方面的巨大潜力,并且设想了更多的商业产品。

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