In vivo confocal microscopy (IVCM) allows detailed examination of the corneal nerves. Damage to V-1 can result in corneal anaesthesia and neurotrophic keratitis. It is not clear whether corneal anaesthesia is related to loss of nerves in the sub-basal plexus or not. We present evidence from patients with uniocular corneal anaesthesia and a normal sub-basal plexus demonstrating a lack of such correlation.
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