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首页> 外文期刊>ORL: Journal for oto-rhino-laryngology and its borderlands >Current Concepts in Therapy of Chronic Rhinosinusitis and Nasal Polyposis.
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Current Concepts in Therapy of Chronic Rhinosinusitis and Nasal Polyposis.

机译：慢性鼻-鼻窦炎和鼻息肉治疗的最新概念。

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The exact pathophysiological mechanisms leading to chronic rhinosinusitis (CRS) still to a large extent remain obscure. However, recently there has been some progress in elucidating the etiology of nasal polyposis, especially regarding tissue eosinophilia as well as the role of aspirin intolerance and eicosanoid mediators. Endonasal sinus surgery has evolved to be the treatment of choice in CRS and nasal polyposis in all cases where conservative treatment has failed or resulted in only a partial or temporary relief. Today, state of the art in surgical technique includes the ability to combine microscopic and endoscopic procedures. Regardless of technical advances like powered instrumentation or computer-aided surgery, in a modern protocol, surgical therapy can offer only one option within a complex and individually tailored therapeutical concept. This review discusses current concepts and new developments in the diagnosis and treatment of CRS and nasal polyposis. Copyright (c) 2005 S. Karger AG, Basel.
机译：导致慢性鼻-鼻窦炎（CRS）的确切病理生理机制仍在很大程度上尚不清楚。但是，最近在阐明鼻息肉的病因方面取得了一些进展，特别是在组织嗜酸性粒细胞增多以及阿司匹林耐受性和类花生酸介体的作用方面。在保守治疗失败或仅导致部分或暂时缓解的所有情况下，鼻内窦手术已发展成为CRS和鼻息肉病的首选治疗方法。如今，外科技术的最新发展包括将显微和内窥镜手术相结合的能力。不管电动仪器或计算机辅助手术等技术进步如何，在现代方案中，手术疗法只能在复杂且个性化的治疗概念中提供一种选择。这篇综述讨论了CRS和鼻息肉的诊断和治疗中的当前概念和新发展。版权所有（c）2005 S.Karger AG，巴塞尔。

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