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Opioids causing a back up in the pediatric intensive care unit? No solution yet.

机译:阿片类药物在小儿重症监护病房中引起备份吗?尚无解决方案。

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摘要

The major limitation in this study is the attempted use of a control group. Although this group was matched by age and weight, they were much different from the treatment group, most notably in the total opioid dose received, the presumed etiology of the constipation. The control group received more than three times the dose of opioids than the treatment group. Although there are data suggesting that the needed dose of oral nal-oxone may be independent of the dose of opioid being administered (7), clearly this difference in the amount of opioid received diminishes the value of the control group as a true comparison.
机译:本研究的主要局限性是试图使用对照组。尽管该组按年龄和体重进行匹配,但它们与治疗组有很大不同,最显着的是所接受的阿片类药物的总剂量,便秘的病因学。对照组接受的阿片类药物剂量是治疗组的三倍以上。尽管有数据表明口服纳洛酮的所需剂量可能与所服用的阿片类药物的剂量无关(7),但显然,阿片类药物摄入量的这种差异降低了对照组的价值,作为真正的比较。

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