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首页> 外文学位 >The effects of naltrexone on repressive coping and disclosure of emotional material: A test of the opioid-peptide theory of repression/hypertension.
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The effects of naltrexone on repressive coping and disclosure of emotional material: A test of the opioid-peptide theory of repression/hypertension.

机译：纳曲酮对压抑应对和情绪物质披露的影响：阿片肽抑制/高血压理论的检验。

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摘要

A relationship between hypertension and repression has long been observed in the psychological literature. Those who exhibit repressive coping styles also tend to exhibit elevated blood pressure levels. Classically, this relationship has been explained by emphasizing the role of repression in elevating, through unknown mechanisms, blood pressure. Recent research, however, suggests that the directionality of this relationship may be reversed, and high blood pressure, through baroreceptor-mediated, endogenous-opioid activity, may result in repressive phenomena. The present study tests this hypothesis by comparing the disclosure of 8 normotensives and 10 hypertensives after receiving either the opioid antagonist naltrexone or a placebo. Administration of the drug or placebo was double-blind and randomized across 4 laboratory visits. Following absorption of the drug, participants verbally described their mood, conflicts, stressors, and concerns. Following the verbal narrative, participants completed measures of repressive coping style, disclosure, mood, and self-perceptions. To accommodate for the small sample size, planned comparisons were used for analyses. Specifically, the hypothesis was tested that naltrexone would significantly alter dependent measures, in the direction of higher disclosure and less repression, in hypertensive subjects only. Results supported the hypothesis. Significantly greater disclosure and significantly less repression were exhibited by hypertensives in the drug sessions versus placebo sessions. The drug condition had no effect on the self-report of normotensives. The results provide initial evidence for the role of endogenous opioids in repression and hypertension.
机译：长期以来，在心理学文献中已经观察到高血压与镇压之间的关系。表现出压抑应对方式的人也倾向于表现出升高的血压水平。经典地，通过强调抑制通过未知机制升高血压的作用来解释这种关系。然而，最近的研究表明，这种关系的方向性可能会逆转，并且通过压力感受器介导的内源性阿片类药物活动引起的高血压可能会导致抑制现象。本研究通过比较接受阿片拮抗剂纳曲酮或安慰剂后的8个血压正常者和10个高血压者的披露来检验该假设。药物或安慰剂的给药是双盲的，并且在4次实验室访问中随机分配。吸收药物后，参与者口头描述他们的情绪，冲突，压力和关注点。在口头叙述之后，参与者完成了压抑应对方式，披露，情绪和自我认知的测量。为了适应较小的样本量，使用了计划的比较进行分析。具体而言，对假说进行了检验，即纳曲酮仅在高血压受试者中会朝着更高披露和更少压抑的方向显着改变依赖的措施。结果支持该假设。与安慰剂治疗相比，药物治疗中高血压患者的披露显着增加，抑制作用显着降低。药物状况对血压正常者的自我报告没有影响。该结果为内源性阿片类药物在抑制和高血压中的作用提供了初步证据。

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  • 作者

    Younger, Jarred Wayne.;

  • 作者单位

    The University of Tennessee.;

  • 授予单位 The University of Tennessee.;
  • 学科 Psychology Psychobiology.; Psychology Clinical.
  • 学位 Ph.D.
  • 年度 2003
  • 页码 83 p.
  • 总页数 83
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 心理学;医学心理学、病理心理学;
  • 关键词

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