首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Effects of naltrexone on repressive coping and disclosure of emotional material: a test of the opioid-peptide hypothesis of repression and hypertension.
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Effects of naltrexone on repressive coping and disclosure of emotional material: a test of the opioid-peptide hypothesis of repression and hypertension.

机译:纳曲酮对压抑应对和情绪物质披露的影响:阿片肽假设抑制和高血压的检验。

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OBJECTIVE: The present study was designed to assess the role of endogenous opioids in the relationship of hypertension to repressive coping. METHODS: Ten hypertensive and 8 normotensive males were given either the opioid antagonist naltrexone or placebo in a randomized, double-blind fashion over the course of four laboratory sessions. Measures of repression and disclosure were completed and blood pressure was assessed during a laboratory stressor protocol. RESULTS: Opioid antagonism reduced repression and increased disclosure only in the hypertensive group. Also, opioid antagonism increased stress-related systolic blood pressure only in the hypertensive group. CONCLUSION: The results support the hypothesis that endogenous opioid dysregulation underlies both hypertension and repressive phenomena.
机译:目的:本研究旨在评估内源性阿片类药物在高血压与抑制性应对之间的作用。方法:在四个实验室会议中,以随机,双盲方式给10位高血压男性和8位血压正常的男性服用了阿片类药物拮抗剂纳曲酮或安慰剂。压抑和泄漏的措施已经完成,并在实验室应激试验方案中评估了血压。结果:阿片类药物拮抗作用仅在高血压组中降低了抑制作用,并增加了披露。同样,仅在高血压组中,阿片类药物拮抗作用会增加与压力相关的收缩压。结论:该结果支持以下假设:内源性阿片类药物失调是高血压和抑制现象的基础。

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