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Immunogenicity of liposomes and iscoms containing the major outer membrane protein of Neisseria gonorrhoeae: influence of protein content and liposomal bilayer composition.

机译:淋病奈瑟氏球菌主要外膜蛋白的脂质体和iscoms的免疫原性:蛋白含量和脂质体双层组成的影响。

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摘要

The influences of Neisseria gonorrhoeae protein IB content and bilayer composition of liposomes and protein content of iscoms on immunogenicity were investigated. Changes in the protein content of liposomes did not influence the immunoglobulin G response, whereas the response was lowered when the amount of protein in iscoms was increased. Bilayer composition only influenced the primary immunoglobulin G response; immunological memory was not affected.
机译:考察了淋病奈瑟氏球菌蛋白IB含量,脂质体双层组成和胰岛蛋白酶的含量对免疫原性的影响。脂质体蛋白质含量的变化不影响免疫球蛋白G的反应,而当iscoms中蛋白质的量增加时,反应降低。双层成分仅影响原发性免疫球蛋白G反应;免疫记忆不受影响。

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