首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >Does long-term lactation protect premenopausal women against hypertension risk? A Korean women's cohort study.
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Does long-term lactation protect premenopausal women against hypertension risk? A Korean women's cohort study.

机译:长期哺乳可以保护绝经前妇女免受高血压的威胁吗?一项韩国女性队列研究。

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BACKGROUND: Little is known about the long-term effect of lactation on maternal cardiovascular health except for a few animal or human experimental studies. The objective of this study was to examine the effects of lactation on the incidence of hypertension in premenopausal women. METHODS: The data were derived from a cohort study with 6 years follow-up (1995-2000). The cohort was composed of 177,749 Korean premenopausal women, aged 20-59, who had medical evaluations in 1992 and 1994. During the follow-up, blood pressure was measured as part of the 1996, 1998, and 2000 periodic examinations. RESULTS: In multivariate Cox proportional hazard models, lactation decreased the risk of hypertension (risk ratio, 0.92; 95% confidence interval, 0.90-0.96). Compared with women who with no history of lactation, 1-6 months of lactation decreased the risk of hypertension (RR, 0.90; 95% CI, 0.87-0.93), as did 7-12 months (RR, 0.92; 95% CI, 0.87-0.98) or 13-18 months (RR, 0.93; 95% CI, 0.86-0.99). In particular, the coexistence of obesity and no lactation increased the risk of hypertension (P for interaction = 0.028). CONCLUSION: This finding suggests that lactation may be a protective factor against hypertension among premenopausal women.
机译:背景:除了一些动物或人体实验研究外,关于泌乳对孕妇心血管健康的长期影响知之甚少。这项研究的目的是检查哺乳期对绝经前女性高血压发病率的影响。方法:数据来自一项为期6年的随访研究(1995-2000)。该队列由177,749名韩国绝经前妇女组成,年龄在20-59岁之间,分别在1992年和1994年进行了医学评估。在随访期间,对血压进行了测量,这是1996年,1998年和2000年定期检查的一部分。结果:在多变量Cox比例风险模型中,泌乳降低了高血压的风险(风险比为0.92; 95%置信区间为0.90-0.96)。与没有哺乳史的女性相比,哺乳1-6个月降低了患高血压的风险(RR,0.90; 95%CI,0.87-0.93),而7-12个月(RR,0.92; 95%CI, 0.87-0.98)或13-18个月(RR,0.93; 95%CI,0.86-0.99)。特别是,肥胖和不哺乳并存​​会增加患高血压的风险(相互作用P = 0.028)。结论:该发现提示泌乳可能是绝经前女性高血压的保护因素。

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